Arginase II (ARG2) Antibody – Rabbit Polyclonal

ARG2: May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. Belongs to the arginase family.

Protein type: EC 3.5.3.1; Mitochondrial; Amino Acid Metabolism - arginine and proline; Hydrolase

Cellular Component: mitochondrion

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; hydrolase activity; metal ion binding; arginase activity; nitric-oxide synthase binding

Biological Process: striated muscle contraction; negative regulation of nitric-oxide synthase activity; arginine metabolic process; arginine catabolic process to ornithine; negative regulation of striated muscle contraction; urea cycle