Rat Anti-PLVAP Monoclonal Antibody – Cat# MBS214381

PLVAP Antibody – Rat Monoclonal

Name: PLVAP Antibody; Monoclonal; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS214381
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS214381

Rat anti Mouse PLVAP antibody, clone MECA-32 recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae… More details

$580 / 0.25 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PLVAP, Monoclonal Antibody

Full Product Name

RAT ANTI MOUSE PLVAP

Product Gene Name

anti-PLVAP antibody

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

MECA-32

Host

Rat

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1.0mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

49,933 Da

3D Structure

ModBase 3D Structure for Q91VC4

Perservative Stabilisers

0.09% Sodium Azide (NaN3)
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Fusion Partners

Spleen cells from immunised rat were fused with cells of the Sp2/0 myeloma cell line.
Buffer Solution||Phosphate buffered saline

Target Species

Mouse

Applications Tested/Suitable for anti-PLVAP antibody

Immunohistology Frozen, Flow cytometry (FC/FACS)

Application Notes for anti-PLVAP antibody

Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Immunohistology - Frozen: Minimum Dilution: 1/25; Maximum Dilution: 1/100

Other Notes

Small volumes of anti-PLVAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLVAP purchase

MBS214381 is an antibody targeting PLVAP. Also known as RAT ANTI MOUSE PLVAP. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for PLVAP. It may not necessarily be applicable to this product.

NCBI GI #

255522953

NCBI GeneID

84094

NCBI Accession #

NP_115774.2

UniProt Primary Accession #

Q91VC4

UniProt Secondary Accession #

Q99JB1

UniProt Related Accession #

Q91VC4

GenBank Nucleotide #

NM_032398.2

NCBI Official Full Name

plasmalemma vesicle-associated protein

NCBI Official Synonym Full Names

plasmalemma vesicle associated protein

NCBI Official Symbol

Plvap

NCBI Official Synonym Symbols

Pv1; MECA32

UniProt Protein Name

Plasmalemma vesicle-associated protein

UniProt Synonym Protein Names

MECA-32 antigen; Plasmalemma vesicle protein 1; PV-1

Protein Family

Plasmalemma vesicle-associated protein

UniProt Gene Name

Plvap

UniProt Synonym Gene Names

Pv1; PV-1

UniProt Entry Name

PLVAP_MOUSE

NCBI Protein Information

plasmalemma vesicle-associated protein; MECA-32 antigen; plasmalemma vesicle protein 1

UniProt Comments for PLVAP

PLVAP: Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.

Protein type: Cell surface; Membrane protein, integral

Cellular Component: cell surface; membrane; cytoplasm; integral to membrane; plasma membrane; caveola; intracellular

Molecular Function: protein homodimerization activity

Biological Process: positive regulation of cellular extravasation; tumor necrosis factor-mediated signaling pathway; MAPKKK cascade

Research Articles on PLVAP

1. PV1 is involved in the tumor angiogenesis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLVAP antibody

Reference Product	PubMed Publications
Pecam1 antibody	>3 publications with PLVAP and Pecam1
Cldn5 antibody	>1 publications with PLVAP and Cldn5

Diseases associated with anti-PLVAP antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with PLVAP and Nervous System Diseases
Brain Diseases Antibodies	>4 publications with PLVAP and Brain Diseases
Disease Models, Animal Antibodies	>4 publications with PLVAP and Disease Models, Animal
Inflammation Antibodies	>3 publications with PLVAP and Inflammation
Necrosis Antibodies	>3 publications with PLVAP and Necrosis
Kidney Diseases Antibodies	>2 publications with PLVAP and Kidney Diseases
Movement Disorders Antibodies	>1 publications with PLVAP and Movement Disorders
Carcinoma, Hepatocellular Antibodies	>1 publications with PLVAP and Carcinoma, Hepatocellular
Fibrosis Antibodies	>1 publications with PLVAP and Fibrosis

Organs/Tissues associated with anti-PLVAP antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>7 publications with PLVAP and Brain
Eye Antibodies	>6 publications with PLVAP and Eye
Kidney Antibodies	>4 publications with PLVAP and Kidney
Liver Antibodies	>3 publications with PLVAP and Liver
Lung Antibodies	>2 publications with PLVAP and Lung
Embryonic Tissue Antibodies	>2 publications with PLVAP and Embryonic Tissue
Pancreas Antibodies	>1 publications with PLVAP and Pancreas