Rabbit Anti-RYR1 Polyclonal Antibody – Cat# MBS2144907

Ryanodine Receptor 1, Skeletal (RYR1) Antibody – Rabbit Polyclonal

Name: RYR1 Antibody; Polyclonal; Rabbit; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2144907
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2144907

MBS2144907 is an antibody targeting RYR1. Also known as Biotin-Linked Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1). Reactive in Rat. Host: Rabbit. More details

$235 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ryanodine Receptor 1, Skeletal (RYR1), Polyclonal Antibody

Full Product Name

Biotin-Linked Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)

Product Gene Name

anti-RYR1 antibody

Product Synonym Names

Ryanodine Receptor 1, Skeletal; CCO; MHS; MHS1; RYDR; RYR; SKRR; Central Core Disease Of Muscle; Skeletal muscle calcuM release channel

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Rat

Form/Format

Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Purity/Purification

Affinity Chromatography

Concentration

>=0.5mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)

Preparation and Storage

Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.

Matching Pairs

Antibody: RYR1 (MBS2144907)
Immunogen: RYR1 (MBS2124570)

Matching Pairs

Unconjugated Antibody: RYR1 (MBS2152804)
Biotin Conjugated Antibody: RYR1 (MBS2144907)

Immunogen Sequence Positions

His99~Cys394

3D Structure

ModBase 3D Structure for F1LMY4

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Conjugation

Biotin

Product Categories/Family for anti-RYR1 antibody

Polyclonal Antibodies (Primary Abs); Primary, Biotin-conjugated; Neuro science

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-RYR1 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-RYR1 antibody

WB: 0.2-2ug/mL, 1:250-2500
IHC: 5-20ug/mL, 1:25-100
ICC: 5-20ug/mL, 1:25-100

Other Notes

Small volumes of anti-RYR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RYR1. It may not necessarily be applicable to this product.

UniProt Primary Accession #

F1LMY4

UniProt Protein Name

Ryanodine receptor 1

UniProt Synonym Protein Names

Skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; Skeletal muscle-type ryanodine receptor; Type 1 ryanodine receptor

Protein Family

Ryanodine receptor

UniProt Gene Name

Ryr1

UniProt Synonym Gene Names

RYR-1; RyR1

UniProt Comments for RYR1

Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.