Rat Anti-Ly-6A/E Monoclonal Antibody – Cat# MBS214531

Ly-6A/E Antibody – Rat Monoclonal

Name: Ly-6A/E Antibody; Monoclonal; Rat; MyBioSource
Brand: MyBioSource
SKU: MBS214531
Price: 485 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS214531

Rat anti Mouse Ly-6A/E antibody, clone D7 recognises members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically, it recognises Ly-6A.2 and Ly-6E.1. Ly-6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Ly-6A/E, Monoclonal Antibody

Full Product Name

RAT ANTI MOUSE Ly-6A/E:FITC

Product Gene Name

anti-Ly-6A/E antibody

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

Host

Rat

Form/Format

FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

Concentration

IgG concentration 0.5mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

14,377 Da

3D Structure

ModBase 3D Structure for P05533

Perservative Stabilisers

0.09% Sodium Azide
Preparation||Purified IgG prepared from ascites or tissue culture supernatant

Buffer Solution

Phosphate buffered saline

Target Species

Mouse

Applications Tested/Suitable for anti-Ly-6A/E antibody

Flow cytometry (FC/FACS)

Application Notes for anti-Ly-6A/E antibody

Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. This may be reduced by using SeroBlock FcR.
Flow Cytometry: Minimum Dilution: 1/5; Maximum Dilution: 1/10

Other Notes

Small volumes of anti-Ly-6A/E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ly-6A/E purchase

MBS214531 is an antibody targeting Ly-6A/E. Also known as RAT ANTI MOUSE Ly-6A/E:FITC. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for Ly-6A/E. It may not necessarily be applicable to this product.

NCBI GI #

406855394

NCBI GeneID

110454

NCBI Accession #

NP_001258345.1

UniProt Primary Accession #

P05533

UniProt Secondary Accession #

Q8BPD0

UniProt Related Accession #

P05533

GenBank Nucleotide #

NM_001271416.1

NCBI Official Full Name

lymphocyte antigen 6A-2/6E-1

NCBI Official Synonym Full Names

lymphocyte antigen 6 complex, locus A

NCBI Official Symbol

Ly6a

NCBI Official Synonym Symbols

TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1

UniProt Protein Name

Lymphocyte antigen 6A-2/6E-1

UniProt Synonym Protein Names

Stem cell antigen 1; SCA-1; T-cell-activating protein; TAP

UniProt Gene Name

Ly6a

UniProt Synonym Gene Names

Ly6; Ly-6A.2/Ly-6E.1; SCA-1; TAP

UniProt Entry Name

LY6A_MOUSE

NCBI Protein Information

lymphocyte antigen 6A-2/6E-1; T-cell-activating protein; stem cell antigen 1

UniProt Comments for Ly-6A/E

Ly6A: T-cell activation.

Protein type: Cell surface

Cellular Component: membrane; plasma membrane; intracellular; external side of plasma membrane

Research Articles on Ly-6A/E

1. The more aggressive behavior of Ly6a/Sca-1 expressing leukemias is due at least in part to greater capacity to degrade microenvironmental stroma and invade tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Ly-6A/E antibody

Reference Product	PubMed Publications
Cd34 antibody	>77 publications with Ly-6A/E and Cd34
Ptprc antibody	>64 publications with Ly-6A/E and Ptprc
Cd4 antibody	>21 publications with Ly-6A/E and Cd4
Cd44 antibody	>20 publications with Ly-6A/E and Cd44
Flt3 antibody	>12 publications with Ly-6A/E and Flt3
Cd5 antibody	>3 publications with Ly-6A/E and Cd5

Diseases associated with anti-Ly-6A/E antibody

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>63 publications with Ly-6A/E and Disease Models, Animal
Inflammation Antibodies	>25 publications with Ly-6A/E and Inflammation
Fibrosis Antibodies	>16 publications with Ly-6A/E and Fibrosis
Arteriosclerosis Antibodies	>14 publications with Ly-6A/E and Arteriosclerosis
Neoplasms, Experimental Antibodies	>14 publications with Ly-6A/E and Neoplasms, Experimental
Necrosis Antibodies	>11 publications with Ly-6A/E and Necrosis
Carcinoma Antibodies	>9 publications with Ly-6A/E and Carcinoma
Hyperplasia Antibodies	>8 publications with Ly-6A/E and Hyperplasia
Hypertrophy Antibodies	>6 publications with Ly-6A/E and Hypertrophy
Lung Injury Antibodies	>6 publications with Ly-6A/E and Lung Injury

Organs/Tissues associated with anti-Ly-6A/E antibody

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>256 publications with Ly-6A/E and Bone Marrow
Blood Antibodies	>231 publications with Ly-6A/E and Blood
Muscle Antibodies	>114 publications with Ly-6A/E and Muscle
Spleen Antibodies	>71 publications with Ly-6A/E and Spleen
Heart Antibodies	>68 publications with Ly-6A/E and Heart
Liver Antibodies	>43 publications with Ly-6A/E and Liver
Lung Antibodies	>36 publications with Ly-6A/E and Lung
Embryonic Tissue Antibodies	>30 publications with Ly-6A/E and Embryonic Tissue
Connective Tissue Antibodies	>23 publications with Ly-6A/E and Connective Tissue
Skin Antibodies	>20 publications with Ly-6A/E and Skin