Mouse Anti-CD106 Monoclonal Antibody – Cat# MBS214615

KM-H2 cells stained with Mouse anti Human CD106 (MBS213194)

CD106 Antibody – Mouse Monoclonal

Name: CD106 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS214615
Price: 510 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS214615

Mouse anti Human CD106 antibody, clone 1.G11B1 recognizes human VCAM-1, a 110kD molecule whose ligand is VLA4. The antigen is expressed on activated endothelial cells and on some tissue macrophages, bone marrow fibroblasts and myoblasts. Mouse anti Human… More details

$510 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD106, Monoclonal Antibody

Full Product Name

MOUSE ANTI HUMAN CD106:FITC

Product Gene Name

anti-CD106 antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

1.G11B1

Host

Mouse

Form/Format

FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

Concentration

IgG concentration 0.1mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

74,346 Da

OMIM

192225

3D Structure

ModBase 3D Structure for P19320

Perservative Stabilisers

0.09% Sodium Azide
0.1% Bovine Serum Albumin
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Buffer Solution

Phosphate buffered saline

Target Species

Human

Applications Tested/Suitable for anti-CD106 antibody

Flow cytometry (FC/FACS)

Application Notes for anti-CD106 antibody

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10

Other Notes

Small volumes of anti-CD106 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD106 purchase

MBS214615 is an antibody targeting CD106. Also known as MOUSE ANTI HUMAN CD106:FITC. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD106. It may not necessarily be applicable to this product.

NCBI GI #

4507875

NCBI GeneID

7412

NCBI Accession #

NP_001069.1

UniProt Primary Accession #

P19320

UniProt Secondary Accession #

Q6NUP8; A8K6R7; B4DKS4; E9PDD1

UniProt Related Accession #

P19320

GenBank Nucleotide #

NM_001078.3

NCBI Official Full Name

vascular cell adhesion protein 1 isoform a

NCBI Official Synonym Full Names

vascular cell adhesion molecule 1

NCBI Official Symbol

VCAM1

NCBI Official Synonym Symbols

CD106; INCAM-100

UniProt Protein Name

Vascular cell adhesion protein 1

UniProt Synonym Protein Names

INCAM-100; CD_antigen: CD106

Protein Family

Vascular cell adhesion protein

UniProt Gene Name

VCAM1

UniProt Synonym Gene Names

L1CAM; V-CAM 1; VCAM-1

UniProt Entry Name

VCAM1_HUMAN

NCBI Protein Information

vascular cell adhesion protein 1; CD106 antigen

NCBI Summary for CD106

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

UniProt Comments for CD106

VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p32-p31

Cellular Component: Golgi apparatus; extracellular space; microvillus; cell surface; endoplasmic reticulum; early endosome; integral to membrane; apical part of cell; plasma membrane; podosome; sarcolemma; external side of plasma membrane; filopodium

Molecular Function: integrin binding; amine oxidase activity; cell adhesion molecule binding

Biological Process: response to nicotine; extracellular matrix organization and biogenesis; chronic inflammatory response; regulation of immune response; viral reproduction; cytokine and chemokine mediated signaling pathway; cell-matrix adhesion; heart development; response to lipopolysaccharide; heterophilic cell adhesion; leukocyte adhesion; response to ethanol; response to zinc ion; B cell differentiation; membrane to membrane docking; response to hypoxia; positive regulation of T cell proliferation; amine metabolic process; response to ionizing radiation; leukocyte tethering or rolling; cell adhesion; response to nutrient; acute inflammatory response; aging

Research Articles on CD106

1. Data show that VCAM-1 (CD106) physically associates with CD44 antigen.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD106 antibody

Reference Product	PubMed Publications
CD44 antibody	>14 publications with CD106 and CD44
ITGA4 antibody	>10 publications with CD106 and ITGA4
ITGB2 antibody	>6 publications with CD106 and ITGB2
ITGB1 antibody	>3 publications with CD106 and ITGB1
VEGFA antibody	>3 publications with CD106 and VEGFA
SRC antibody	>2 publications with CD106 and SRC
ITGAD antibody	>1 publications with CD106 and ITGAD

Pathways associated with anti-CD106 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cellular Roles Of Anthrax Toxin Pathway antibodies	Cellular Roles Of Anthrax Toxin Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram

Diseases associated with anti-CD106 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>86 publications with CD106 and Inflammation
Cardiovascular Diseases Antibodies	>54 publications with CD106 and Cardiovascular Diseases
Necrosis Antibodies	>50 publications with CD106 and Necrosis
Atherosclerosis Antibodies	>42 publications with CD106 and Atherosclerosis
Kidney Diseases Antibodies	>13 publications with CD106 and Kidney Diseases
Hypertension Antibodies	>12 publications with CD106 and Hypertension
Heart Diseases Antibodies	>11 publications with CD106 and Heart Diseases
Myocardial Ischemia Antibodies	>9 publications with CD106 and Myocardial Ischemia
Anemia Antibodies	>8 publications with CD106 and Anemia
Myocardial Infarction Antibodies	>7 publications with CD106 and Myocardial Infarction

Organs/Tissues associated with anti-CD106 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>202 publications with CD106 and Vascular
Blood Antibodies	>122 publications with CD106 and Blood
Kidney Antibodies	>24 publications with CD106 and Kidney
Embryonic Tissue Antibodies	>22 publications with CD106 and Embryonic Tissue
Brain Antibodies	>20 publications with CD106 and Brain
Heart Antibodies	>17 publications with CD106 and Heart
Liver Antibodies	>15 publications with CD106 and Liver
Lung Antibodies	>13 publications with CD106 and Lung
Skin Antibodies	>8 publications with CD106 and Skin
Placenta Antibodies	>8 publications with CD106 and Placenta