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Vasular Cell Adhesion Moleule 1 (VCAM1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2146329
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MBS2146329 is an antibody targeting VCAM1. Also known as Cy3-Linked Monoclonal Antibody to Vasular Cell Adhesion Moleule 1 (VCAM1). Reactive in Mouse. Host: Mouse. More details

$345 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Vasular Cell Adhesion Moleule 1 (VCAM1), Monoclonal Antibody
Full Product Name
Cy3-Linked Monoclonal Antibody to Vasular Cell Adhesion Moleule 1 (VCAM1)
Product Gene Name
anti-VCAM1 antibody
Product Synonym Names
Vasular Cell Adhesion Moleule 1; CD106; INCAM-100; L1CAM
Clonality
Monoclonal
Isotype
IgG2b Kappa
Clone Number
C13
Host
Mouse
Species Reactivity
Mouse
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Protein A + Protein G affinity chromatography
Concentration
>=1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Matching Pairs
Antibody: VCAM1 Clone #C13 (MBS2146329)
Immunogen: VCAM1 (MBS2122648)
Matching Pairs
Unconjugated Antibody: VCAM1 Clone #C13 (MBS2152646)
Cy3 Conjugated Antibody: VCAM1 Clone #C13 (MBS2146329)
Molecular Weight
38,372 Da
Immunogen Sequence Positions
Val110~Ser318
3D Structure
ModBase 3D Structure for P29533
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
Cy3

Product Categories/Family for anti-VCAM1 antibody

Monoclonal Antibodies (Primary Abs); Primary, Cy3-conjugated; CD & Adhesion moleule
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-VCAM1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-VCAM1 antibody
WB: 0.01-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-VCAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VCAM1. It may not necessarily be applicable to this product.

NCBI GI #
170295823
NCBI GeneID
22329
NCBI Accession #
NP_035823.3
UniProt Primary Accession #
P29533
UniProt Related Accession #
P29533
GenBank Nucleotide #
NM_011693.3
NCBI Official Full Name
vascular cell adhesion protein 1
NCBI Official Synonym Full Names
vascular cell adhesion molecule 1
NCBI Official Symbol
Vcam1
NCBI Official Synonym Symbols
CD106; Vcam-1
UniProt Protein Name
Vascular cell adhesion protein 1
UniProt Synonym Protein Names
CD_antigen: CD106
Protein Family
Vascular cell adhesion protein
UniProt Gene Name
Vcam1
UniProt Synonym Gene Names
Vcam-1; V-CAM 1; VCAM-1
UniProt Entry Name
VCAM1_MOUSE
NCBI Protein Information
vascular cell adhesion protein 1

UniProt Comments for VCAM1

VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Cellular Component: apical part of cell; cell surface; early endosome; endoplasmic reticulum; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; microvillus; podosome; sarcolemma

Molecular Function: amine oxidase activity; cell adhesion molecule binding; integrin binding

Biological Process: amine metabolic process; cell adhesion; cell-matrix adhesion; heart development; heterophilic cell adhesion; leukocyte adhesion; leukocyte tethering or rolling; positive regulation of T cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-VCAM1 antibody

 Products by Pathway  Pathway Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 AGE-RAGE Signaling Pathway In Diabetic Complications antibodies  AGE-RAGE Signaling Pathway In Diabetic Complications Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram

Diseases associated with anti-VCAM1 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >118 publications with VCAM1 and Inflammation
 Cardiovascular Diseases Antibodies  >76 publications with VCAM1 and Cardiovascular Diseases
 Necrosis Antibodies  >59 publications with VCAM1 and Necrosis
 Atherosclerosis Antibodies  >56 publications with VCAM1 and Atherosclerosis
 Heart Diseases Antibodies  >20 publications with VCAM1 and Heart Diseases
 Kidney Diseases Antibodies  >19 publications with VCAM1 and Kidney Diseases
 Fibrosis Antibodies  >14 publications with VCAM1 and Fibrosis
 Lung Diseases Antibodies  >13 publications with VCAM1 and Lung Diseases
 Hypertension Antibodies  >13 publications with VCAM1 and Hypertension
 Myocardial Ischemia Antibodies  >10 publications with VCAM1 and Myocardial Ischemia

Organs/Tissues associated with anti-VCAM1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >27 publications with VCAM1 and Kidney
 Spleen Antibodies  >6 publications with VCAM1 and Spleen
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