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Dermcidin (DCD) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2146843
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MBS2146843 is an antibody targeting DCD. Also known as APC-Linked Monoclonal Antibody to Dermcidin (DCD). Reactive in Human. Host: Mouse. More details

$345 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Dermcidin (DCD), Monoclonal Antibody
Full Product Name
APC-Linked Monoclonal Antibody to Dermcidin (DCD)
Product Gene Name
Product Synonym Names
Dermcidin; HCAP; AIDD; DCD1; DSEP; PIF; Proteolysis Inducing Factor; Preproteolysin; Diffusible Survival/Evasion Peptide; Survival Promoting Peptide
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
C6
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Protein A + Protein G affinity chromatography
Concentration
>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Matching Pairs
Matching Pairs
Unconjugated Antibody: DCD Clone #C6 (MBS2151584)
APC Conjugated Antibody: DCD Clone #C6 (MBS2146843)
Molecular Weight
11,284 Da
Immunogen Sequence Positions
Cys18~Leu110
OMIM
606634
3D Structure
ModBase 3D Structure for P81605
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
APC
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-DCD antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-DCD antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-DCD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DCD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dermcidin isoform 1 preproprotein
NCBI Official Synonym Full Names
dermcidin
NCBI Official Symbol
DCD
NCBI Official Synonym Symbols
PIF; AIDD; DSEP; HCAP; DCD-1
UniProt Protein Name
Dermcidin
UniProt Synonym Protein Names
Preproteolysin
UniProt Gene Name
DCD
UniProt Synonym Gene Names
AIDD; DSEP
UniProt Entry Name
DCD_HUMAN
NCBI Protein Information
dermcidin; preproteolysin; survival promoting peptide; proteolysis inducing factor; diffusible survival/evasion peptide

NCBI Summary for DCD

This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
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UniProt Comments for DCD

DCD: DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; EC 3.4.-.-

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: extracellular region

Molecular Function: peptidase activity

Biological Process: killing of cells of another organism; defense response to bacterium; proteolysis; defense response to fungus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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