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IFN ALPHA (IFNA2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS214798

Mouse anti Human interferon alpha antibody, clone C10F5 recognizes an epitope common to IFN-alpha subtypes A, F, D, I1 and P. Strongest reaction in ELISA is with subtypes alpha F and alpha D. It has an affinity constant of 2.4 x 10-10M. Mouse anti Human… More details

$695 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IFN ALPHA (IFNA2), Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN INTERFERON ALPHA
Product Gene Name
anti-IFNA2 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
C10F5
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
21,550 Da
OMIM
147562
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution
Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-IFNA2 antibody
Immunohistology Frozen, ELISA (EIA)

Other Notes

Small volumes of anti-IFNA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFNA2 purchase

MBS214798 is an antibody targeting IFNA2. Also known as MOUSE ANTI HUMAN INTERFERON ALPHA. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNA2. It may not necessarily be applicable to this product.

NCBI GI #
11067751
NCBI GeneID
3440
NCBI Accession #
NP_000596.2
UniProt Secondary Accession #
P01564; Q14606; Q6DJX8; Q96KI6; H2DF54; H2DF55
UniProt Related Accession #
P01563
GenBank Nucleotide #
NM_000605.3
NCBI Official Full Name
interferon alpha-2
NCBI Official Synonym Full Names
interferon, alpha 2
NCBI Official Symbol
IFNA2
NCBI Official Synonym Symbols
IFNA; INFA2; IFNA2B; IFN-alphaA
UniProt Protein Name
Interferon alpha-2
UniProt Synonym Protein Names
Interferon alpha-A; LeIF A
Protein Family
Interferon
UniProt Gene Name
IFNA2
UniProt Synonym Gene Names
IFNA2A; IFNA2B; IFNA2C; IFN-alpha-2; LeIF A
UniProt Entry Name
IFNA2_HUMAN
NCBI Protein Information
interferon alpha-2; IFN-alpha-2; alpha-2a interferon; interferon alpha 2a; interferon alpha 2b; interferon alpha A; leIF A

NCBI Summary for IFNA2

This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
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UniProt Comments for IFNA2

IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family.

Protein type: Membrane protein, integral; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space; extracellular region

Molecular Function: protein binding; interferon-alpha/beta receptor binding; cytokine activity

Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; negative regulation of virion penetration into host cell; apoptosis; cytokine and chemokine mediated signaling pathway; innate immune response; blood coagulation; negative regulation of transcription, DNA-dependent; inflammatory response; defense response to virus; negative regulation of T cell differentiation; positive regulation of tyrosine phosphorylation of Stat3 protein
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Research Articles on IFNA2

1. IFN-1ant may be a therapeutic candidate for the treatment of specific viral infections without inducing the immunomodulatory and antiproliferative functions of wild-type IFN.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFNA2 antibody

 Reference Product  PubMed Publications
 IFNAR1 antibody  >403 publications with IFNA2 and IFNAR1
 STAT2 antibody  >288 publications with IFNA2 and STAT2
 IFNAR2 antibody  >200 publications with IFNA2 and IFNAR2
 TYK2 antibody  >161 publications with IFNA2 and TYK2
 IRF9 antibody  >143 publications with IFNA2 and IRF9
 IRF1 antibody  >120 publications with IFNA2 and IRF1
 IL2 antibody  >72 publications with IFNA2 and IL2
 IRF2 antibody  >44 publications with IFNA2 and IRF2
 IFNG antibody  >21 publications with IFNA2 and IFNG
 IFNA5 antibody  >4 publications with IFNA2 and IFNA5

Pathways associated with anti-IFNA2 antibody

 Products by Pathway  Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Hepatitis B Pathway antibodies  Hepatitis B Pathway Diagram

Diseases associated with anti-IFNA2 antibody

 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >2525 publications with IFNA2 and Skin Diseases
 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Antibodies  >1410 publications with IFNA2 and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
 Carcinoma, Renal Cell Antibodies  >1402 publications with IFNA2 and Carcinoma, Renal Cell
 Anemia Antibodies  >888 publications with IFNA2 and Anemia
 Fever Antibodies  >791 publications with IFNA2 and Fever
 Lymphoma, Non-Hodgkin Antibodies  >705 publications with IFNA2 and Lymphoma, Non-Hodgkin
 Neutropenia Antibodies  >651 publications with IFNA2 and Neutropenia
 Fatigue Antibodies  >647 publications with IFNA2 and Fatigue
 Mental Disorders Antibodies  >634 publications with IFNA2 and Mental Disorders
 Thrombocytopenia Antibodies  >610 publications with IFNA2 and Thrombocytopenia
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