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C Reactive Protein (CRP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2149839
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MBS2149839 is an antibody targeting CRP. Also known as PE-Linked Polyclonal Antibody to C Reactive Protein (CRP). Reactive in Mouse. Host: Rabbit. More details

$310 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C Reactive Protein (CRP), Polyclonal Antibody
Full Product Name
PE-Linked Polyclonal Antibody to C Reactive Protein (CRP)
Product Gene Name
anti-CRP antibody
Product Synonym Names
C Reactive Protein; C-RP; PTX1; Pentraxin-Related; Pentraxin 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Matching Pairs
Antibody: CRP (MBS2149839)
Immunogen: CRP (MBS2153877)
Matching Pairs
Unconjugated Antibody: CRP (MBS2152984)
PE Conjugated Antibody: CRP (MBS2149839)
Molecular Weight
25,360 Da
Immunogen Sequence Positions
His20~Ser225
3D Structure
ModBase 3D Structure for P14847
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
PE

Product Categories/Family for anti-CRP antibody

Polyclonal Antibodies (Primary Abs); Primary, PE-conjugated; Tumor immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CRP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-CRP antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-CRP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.

NCBI GI #
408360035
NCBI GeneID
12944
NCBI Accession #
P14847.2
UniProt Primary Accession #
P14847
UniProt Secondary Accession #
E9PZ20
UniProt Related Accession #
P14847
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Symbol
Crp
NCBI Official Synonym Symbols
AI255847
UniProt Protein Name
C-reactive protein
Protein Family
C-reactive protein
UniProt Gene Name
Crp
UniProt Synonym Gene Names
Ptx1
UniProt Entry Name
CRP_MOUSE
NCBI Protein Information
C-reactive protein; C-reactive protein, petaxin related

UniProt Comments for CRP

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: protein homodimerization activity; low-density lipoprotein receptor binding; metal ion binding; complement component C1q binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding

Biological Process: protein polymerization; positive regulation of nitric oxide biosynthetic process; negative regulation of vasodilation; wound healing; positive regulation of superoxide release; acute-phase response; negative regulation of superoxide release; complement activation, classical pathway
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Research Articles on CRP

1. The interactions of CRP and the BBB are a two-phase process, with increased paracellular permeability at a high dose that enables its entry into the CNS and serves to induce reactive gliosis and impair CNS function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CRP antibody

 Reference Product  PubMed Publications
 Il6 antibody  >454 publications with CRP and Il6
 Serpine1 antibody  >316 publications with CRP and Serpine1
 Vegfa antibody  >36 publications with CRP and Vegfa
 Nos3 antibody  >31 publications with CRP and Nos3
 C4bp antibody  >12 publications with CRP and C4bp
 Lep antibody  >9 publications with CRP and Lep
 Selp antibody  >8 publications with CRP and Selp
 Vcam1 antibody  >6 publications with CRP and Vcam1
 Creb3l3 antibody  >1 publications with CRP and Creb3l3

Pathways associated with anti-CRP antibody

 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram

Diseases associated with anti-CRP antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11264 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >8320 publications with CRP and Cardiovascular Diseases
 Infection Antibodies  >4494 publications with CRP and Infection
 Heart Diseases Antibodies  >3980 publications with CRP and Heart Diseases
 Metabolic Diseases Antibodies  >3720 publications with CRP and Metabolic Diseases
 Myocardial Ischemia Antibodies  >3197 publications with CRP and Myocardial Ischemia
 Necrosis Antibodies  >3151 publications with CRP and Necrosis
 Atherosclerosis Antibodies  >2829 publications with CRP and Atherosclerosis
 Arthritis, Rheumatoid Antibodies  >1984 publications with CRP and Arthritis, Rheumatoid
 Pain Antibodies  >1958 publications with CRP and Pain

Organs/Tissues associated with anti-CRP antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1392 publications with CRP and Liver
 Muscle Antibodies  >1142 publications with CRP and Muscle
 Lung Antibodies  >1090 publications with CRP and Lung
 Bone Marrow Antibodies  >286 publications with CRP and Bone Marrow
 Uterus Antibodies  >59 publications with CRP and Uterus
 Embryonic Tissue Antibodies  >57 publications with CRP and Embryonic Tissue
 Thymus Antibodies  >32 publications with CRP and Thymus
 Testis Antibodies  >8 publications with CRP and Testis
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