Mouse Anti-HbA1c Monoclonal Antibody – Cat# MBS2149896

Glycated Hemoglobin A1c (HbA1c) Antibody – Mouse Monoclonal

Name: HbA1c Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2149896
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2149896

MBS2149896 is an antibody targeting HbA1c. Also known as PE-Linked Monoclonal Antibody to Glycated Hemoglobin A1c (HbA1c). Reactive in Human. Host: Mouse. More details

$305 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glycated Hemoglobin A1c (HbA1c), Monoclonal Antibody

Full Product Name

PE-Linked Monoclonal Antibody to Glycated Hemoglobin A1c (HbA1c)

Product Gene Name

anti-HbA1c antibody

Product Synonym Names

Glycated Hemoglobin A1c; Glycosylated Hemoglobin; Hemoglobin A1c; Hb1c; HbAIc; HbAIc

Clonality

Monoclonal

Isotype

IgG1 Kappa

Clone Number

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Purity/Purification

Protein A + Protein G affinity chromatography

Concentration

>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)

Preparation and Storage

Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.

Matching Pairs

Unconjugated Antibody: HbA1c Clone #C5 (MBS2153042)
PE Conjugated Antibody: HbA1c Clone #C5 (MBS2149896)

Molecular Weight

194,811 Da

3D Structure

ModBase 3D Structure for O95602

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Conjugation

Product Categories/Family for anti-HbA1c antibody

Monoclonal Antibodies (Primary Abs); Primary, PE-conjugated

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-HbA1c antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-HbA1c antibody

WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-HbA1c antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HbA1c. It may not necessarily be applicable to this product.

NCBI GI #

103471997

NCBI GeneID

25885

NCBI Accession #

NP_056240.2

UniProt Primary Accession #

O95602

UniProt Secondary Accession #

Q0VG05; Q9UEH0; Q9UFT9; B7Z7T0; D6W5M0

UniProt Related Accession #

O95602

GenBank Nucleotide #

NM_015425.3

NCBI Official Full Name

DNA-directed RNA polymerase I subunit RPA1

NCBI Official Synonym Full Names

polymerase (RNA) I polypeptide A, 194kDa

NCBI Official Symbol

POLR1A

NCBI Official Synonym Symbols

A190; RPA1; RPO14; RPA194; RPO1-4

UniProt Protein Name

DNA-directed RNA polymerase I subunit RPA1

UniProt Synonym Protein Names

A190; DNA-directed RNA polymerase I largest subunit; DNA-directed RNA polymerase I subunit A; RNA polymerase I 194 kDa subunit; RPA194

UniProt Gene Name

POLR1A

UniProt Synonym Gene Names

RNA polymerase I subunit A1; RPA194

UniProt Entry Name

RPA1_HUMAN

NCBI Protein Information

DNA-directed RNA polymerase I subunit RPA1; RNA polymerase I subunit A1; RNA polymerase I 194 kDa subunit; DNA-directed RNA polymerase I subunit A; DNA-directed RNA polymerase I subunit A1; DNA-directed RNA polymerase I largest subunit

UniProt Comments for HbA1c

POLR1A: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. Belongs to the RNA polymerase beta' chain family.

Protein type: Nucleotide Metabolism - pyrimidine; Transferase; Transcription initiation complex; Nucleotide Metabolism - purine; Nucleolus; EC 2.7.7.6

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus; DNA-directed RNA polymerase I complex

Molecular Function: protein binding; DNA binding; zinc ion binding

Biological Process: negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; regulation of gene expression, epigenetic

Disease: Acrofacial Dysostosis, Cincinnati Type

Research Articles on HbA1c

1. SIRT7 knockdown leads to reduced levels of RNA Pol I protein, but not messenger RNA

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-HbA1c antibody

Products by Pathway	Pathway Diagram
Epigenetic Regulation Of Gene Expression Pathway antibodies	Epigenetic Regulation Of Gene Expression Pathway Diagram
Eukaryotic Transcription Initiation Pathway antibodies	Eukaryotic Transcription Initiation Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Integrated Pancreatic Cancer Pathway antibodies	Integrated Pancreatic Cancer Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Negative Epigenetic Regulation Of RRNA Expression Pathway antibodies	Negative Epigenetic Regulation Of RRNA Expression Pathway Diagram
NoRC Negatively Regulates RRNA Expression Pathway antibodies	NoRC Negatively Regulates RRNA Expression Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram

Diseases associated with anti-HbA1c antibody

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>1 publications with HbA1c and Disease Models, Animal

Organs/Tissues associated with anti-HbA1c antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1 publications with HbA1c and Liver
Embryonic Tissue Antibodies	>1 publications with HbA1c and Embryonic Tissue