Mouse Anti-MIP1a Monoclonal Antibody – Cat# MBS2152388

Western Blot; Sample: Rat Bone marrow lysate Primary Ab: 0.6ug/ml Mouse Anti-Rat MIP1a Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (#MBS2086035)

Macrophage Inflammatory Protein 1 Alpha (MIP1a) Antibody – Mouse Monoclonal

Name: MIP1a Antibody; Monoclonal; Mouse; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2152388
Price: 200 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2152388

MBS2152388 is an antibody targeting MIP1a. Also known as Monoclonal Antibody to Macrophage Inflammatory Protein 1 Alpha (MIP1a). Reactive in Rat. Host: Mouse. More details

$200 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Macrophage Inflammatory Protein 1 Alpha (MIP1a), Monoclonal Antibody

Full Product Name

Monoclonal Antibody to Macrophage Inflammatory Protein 1 Alpha (MIP1a)

Product Gene Name

anti-MIP1a antibody

Product Synonym Names

Macrophage Inflammatory Protein 1 Alpha; CCL3; MIP1-A; SCYA3; Chemokine C-C-Motif Ligand 3; Small Inducible Cytokine A3; Homologous To Mouse Mip-1a; Tonsillar Lymphocyte LD78 Alpha Protein

Clonality

Monoclonal

Isotype

IgG1 Kappa

Clone Number

Host

Mouse

Species Reactivity

Rat

Form/Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Purity/Purification

Protein A + Protein G affinity chromatography

Concentration

1mg/mL (lot specific)

Specificity

The antibody is a mouse monoclonal antibody raised against MIP1a. It has been selected for its ability to recognize MIP1a in immunohistochemical staining and western blotting.

Preparation and Storage

Store at 4 degree C for frequent use. Store at -20 degree C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Stable for 12 months if correctly stored.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Matching Pairs

Antibody: MIP1a Clone #C8 (MBS2152388)
Immunogen: MIP1a (MBS2031266)

Matching Pairs

Unconjugated Antibody: MIP1a Clone #C8 (MBS2152388)
HRP Conjugated Antibody: MIP1a Clone #C8 (MBS2141331)

Molecular Weight

10,335 Da

Immunogen Sequence Positions

Ala24~Ala92

3D Structure

ModBase 3D Structure for P50229

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Immunogen

Recombinant Macrophage Inflammatory Protein 1 Alpha (MIP1a)

Product Categories/Family for anti-MIP1a antibody

Monoclonal Antibodies (Primary Abs); Monoclonal antibodies; Cytokine

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-MIP1a antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-MIP1a antibody

WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-MIP1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP1a. It may not necessarily be applicable to this product.

NCBI GI #

40254794

NCBI GeneID

25542

NCBI Accession #

NP_037157.2

UniProt Primary Accession #

P50229

UniProt Secondary Accession #

A1EC87

UniProt Related Accession #

P50229

GenBank Nucleotide #

NM_013025.2

NCBI Official Full Name

C-C motif chemokine 3

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 3

NCBI Official Symbol

Ccl3

NCBI Official Synonym Symbols

Scya3; MIP-1a

UniProt Protein Name

C-C motif chemokine 3

UniProt Synonym Protein Names

Macrophage inflammatory protein 1-alpha; MIP-1-alpha; Small-inducible cytokine A3

Protein Family

B-box domain protein

UniProt Gene Name

Ccl3

UniProt Synonym Gene Names

Mip1a; Scya3; MIP-1-alpha

UniProt Entry Name

CCL3_RAT

NCBI Protein Information

C-C motif chemokine 3; MIP-1-alpha; Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; small inducible cytokine A3; small-inducible cytokine A3

NCBI Summary for MIP1a

mediates monocyte and neutrophil chemotaxis; may play a role in the pathogenesis of acute lung injury [RGD, Feb 2006]

UniProt Comments for MIP1a

Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.

Research Articles on MIP1a

1. Expression levels of CCL3 in the spinal cord are up-regulated following nerve injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MIP1a antibody

Products by Pathway	Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram

Diseases associated with anti-MIP1a antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>893 publications with MIP1a and Inflammation
Necrosis Antibodies	>506 publications with MIP1a and Necrosis
Disease Models, Animal Antibodies	>314 publications with MIP1a and Disease Models, Animal
Lung Diseases Antibodies	>238 publications with MIP1a and Lung Diseases
HIV Infections Antibodies	>188 publications with MIP1a and HIV Infections
Cardiovascular Diseases Antibodies	>173 publications with MIP1a and Cardiovascular Diseases
Hypersensitivity Antibodies	>105 publications with MIP1a and Hypersensitivity
Liver Diseases Antibodies	>95 publications with MIP1a and Liver Diseases
Fibrosis Antibodies	>79 publications with MIP1a and Fibrosis
Pneumonia Antibodies	>72 publications with MIP1a and Pneumonia

Organs/Tissues associated with anti-MIP1a antibody

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>41 publications with MIP1a and Connective Tissue
Adipose Tissue Antibodies	>22 publications with MIP1a and Adipose Tissue
Inner Ear Antibodies	>1 publications with MIP1a and Inner Ear