Mouse Anti-CCL27 Monoclonal Antibody – Cat# MBS2153013

Chemokine (C-X-C Motif) Ligand 27 (CCL27) Antibody – Mouse Monoclonal

Name: CCL27 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2153013
Price: 200 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2153013

MBS2153013 is an antibody targeting CCL27. Also known as Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27). Reactive in Human. Host: Mouse. More details

$200 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Chemokine (C-X-C Motif) Ligand 27 (CCL27), Monoclonal Antibody

Full Product Name

Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27)

Product Gene Name

anti-CCL27 antibody

Product Synonym Names

Chemokine (C-X-C Motif) Ligand 27; CTACK; ILC; SCYA27; ALP; Skinkine; ESkine; PESKY; CTAK; Cutaneous T-Cell Attracting Chemokine; Small Inducible Cytokine Subfamily A Member 27; IL-11 R-alpha-locus chemokine

Clonality

Monoclonal

Isotype

IgG2b Kappa

Clone Number

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Purity/Purification

Protein A + Protein G affinity chromatography

Concentration

1mg/mL (lot specific)

Specificity

The antibody is a mouse monoclonal antibody raised against CCL27. It has been selected for its ability to recognize CCL27 in immunohistochemical staining and western blotting.

Preparation and Storage

Store at 4 degree C for frequent use. Store at -20 degree C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Stable for 12 months if correctly stored.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Matching Pairs

Antibody: CCL27 Clone #C1 (MBS2153013)
Immunogen: CTACK (MBS2011900)

Matching Pairs

Unconjugated Antibody: CCL27 Clone #C1 (MBS2153013)
HRP Conjugated Antibody: CCL27 Clone #C1 (MBS2141966)

Molecular Weight

12,618 Da

Immunogen Sequence Positions

Phe25~Gly112

OMIM

604833

3D Structure

ModBase 3D Structure for Q9Y4X3

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Immunogen

Recombinant Chemokine (C-X-C Motif) Ligand 27 (CCL27)

Product Categories/Family for anti-CCL27 antibody

Monoclonal Antibodies (Primary Abs); Monoclonal antibodies; Cytokine

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-CCL27 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Application Notes for anti-CCL27 antibody

WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-CCL27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL27. It may not necessarily be applicable to this product.

NCBI GI #

5730035

NCBI GeneID

10850

NCBI Accession #

NP_006655.1

UniProt Primary Accession #

Q9Y4X3

UniProt Related Accession #

Q9Y4X3

GenBank Nucleotide #

NM_006664.2

NCBI Official Full Name

C-C motif chemokine 27

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 27

NCBI Official Symbol

CCL27

NCBI Official Synonym Symbols

ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27

UniProt Protein Name

C-C motif chemokine 27

UniProt Synonym Protein Names

CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL27

UniProt Synonym Gene Names

ILC; SCYA27; CTACK

UniProt Entry Name

CCL27_HUMAN

NCBI Protein Information

C-C motif chemokine 27; skinkine; CC chemokine ILC; IL-11 Ralpha-locus chemokine; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; cutaneous T-cell attracting chemokine; cutaneous T-cell-attracting chemokine; small inducible cytokine subfamily

NCBI Summary for CCL27

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Jul 2008]

UniProt Comments for CCL27

CCL27: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity

Biological Process: cell-cell signaling; immune response; chemotaxis

Research Articles on CCL27

1. We show that the adult but not prenatal human keratinocytes produce and release large amounts of CCL27.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCL27 antibody

Reference Product	PubMed Publications
CCR10 antibody	>60 publications with CCL27 and CCR10
CCL20 antibody	>21 publications with CCL27 and CCL20
CXCL10 antibody	>20 publications with CCL27 and CXCL10
CCR7 antibody	>15 publications with CCL27 and CCR7
CCL21 antibody	>14 publications with CCL27 and CCL21
CCR6 antibody	>5 publications with CCL27 and CCR6
CCR5 antibody	>5 publications with CCL27 and CCR5
CCL25 antibody	>5 publications with CCL27 and CCL25
CCBP2 antibody	>4 publications with CCL27 and CCBP2
CXCR5 antibody	>1 publications with CCL27 and CXCR5

Pathways associated with anti-CCL27 antibody

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with anti-CCL27 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>55 publications with CCL27 and Immune System Diseases
Necrosis Antibodies	>33 publications with CCL27 and Necrosis
Skin Neoplasms Antibodies	>16 publications with CCL27 and Skin Neoplasms
Disease Models, Animal Antibodies	>11 publications with CCL27 and Disease Models, Animal
Dermatitis, Allergic Contact Antibodies	>11 publications with CCL27 and Dermatitis, Allergic Contact
Drug-Related Side Effects and Adverse Reactions Antibodies	>6 publications with CCL27 and Drug-Related Side Effects and Adverse Reactions
Nervous System Diseases Antibodies	>5 publications with CCL27 and Nervous System Diseases
Liver Diseases Antibodies	>3 publications with CCL27 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with CCL27 and Liver Neoplasms
Precancerous Conditions Antibodies	>2 publications with CCL27 and Precancerous Conditions

Organs/Tissues associated with anti-CCL27 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>6 publications with CCL27 and Lung
Connective Tissue Antibodies	>4 publications with CCL27 and Connective Tissue
Eye Antibodies	>2 publications with CCL27 and Eye
Testis Antibodies	>2 publications with CCL27 and Testis
Placenta Antibodies	>2 publications with CCL27 and Placenta