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Fc Fragment of IgG Low Affinity Iiib Receptor (FcgR3B) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2153097
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MBS2153097 is an antibody targeting FcgR3B. Also known as FITC-Linked Anti-Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) Monoclonal Antibody. Reactive in Human. Host: Mouse. More details

$200 / 25 Tests +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B), Monoclonal Antibody
Full Product Name
FITC-Linked Anti-Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) Monoclonal Antibody
Product Gene Name
Product Synonym Names
Fc Fragment Of IgG Low Affinity IIIb Receptor; CD16b; CD16-B; FCGR3-B; FCG3; FcgRIII; Low affinity immunogloulin gamma Fc region receptor III-B
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
C2
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Protein A + Protein G affinity chromatography
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at 4 degree C for frequent use, protected from prolonged exposure to light. At -20 degree C for 12 months
Stable for 12 months if correctly stored.
Matching Pairs
Molecular Weight
26,216 Da
Immunogen Sequence Positions
Pro24~Ser203
OMIM
X16863 mRNA
3D Structure
ModBase 3D Structure for O75015
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-FcgR3B antibody
Flow Cytometry (FC/FACS/FCM)
Application Notes for anti-FcgR3B antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Testing Data of anti-FcgR3B antibody

human peripheral blood lymphocytes were stained with 5ul/test mouse Anti-human CD16b Monoclonal Antibody (filled green histogram) or Isotype control antibody (filled red histogram).
Mouse Anti-FcgR3B Monoclonal Antibody – Cat# MBS2153097

Other Notes

Small volumes of anti-FcgR3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FcgR3B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Low affinity immunoglobulin gamma Fc region receptor III-B
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIIb
NCBI Official Symbol
FCGR3B
NCBI Official Synonym Symbols
CD16; FCG3; CD16A; CD16b; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-B
UniProt Synonym Protein Names
Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b
UniProt Gene Name
FCGR3B
UniProt Synonym Gene Names
CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor III-B

NCBI Summary for FcgR3B

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
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UniProt Comments for FcgR3B

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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