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CD240DCE Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS215429

MBS212434 recognises human erythrocytes of normal Rh types but does not recognise Rhnull erythrocytes. MBS212434 reacts with 31kD and 35-52kD proteins which were designated CD240DCE at the 7th leucocyte typing workshop. More details

$245 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD240 (CD240DCE), Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD240DCE
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
BRIC69
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (lot specific)
Specificity
This item recognises human erythrocytes of normal Rh types but does not recognise Rhnull erythrocytes. This item reacts with 31kD and 35-52kD proteins which were designated CD240DCE at the 7th leucocyte typing workshop.
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
26,852 Da
OMIM
111690
3D Structure
ModBase 3D Structure for P18577
Perservative Stabilisers
0.09% Sodium Azide
Immunogen
Human erythrocytes
Buffer Solution||TRIS buffered glycine
Target Species
Human
Applications Tested/Suitable for anti-CD240DCE antibody
Flow cytometry (FC/FACS), Immunoprecipitation (IP)
Application Notes for anti-CD240DCE antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.

Other Notes

Small volumes of anti-CD240DCE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD240DCE purchase

MBS215429 is an antibody targeting CD240DCE. Also known as MOUSE ANTI HUMAN CD240DCE. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD240DCE. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
blood group Rh(CE) polypeptide isoform 1
NCBI Official Synonym Full Names
Rh blood group, CcEe antigens
NCBI Official Symbol
RHCE
NCBI Official Synonym Symbols
RH; RHC; RHE; Rh4; RHPI; RhVI; RH30A; RHIXB; RhVIII; CD240CE; RhIVb(J)
UniProt Protein Name
Blood group Rh(CE) polypeptide
UniProt Synonym Protein Names
Rh polypeptide 1; RhPI; Rh30A; RhIXB; Rhesus C/E antigens; CD_antigen: CD240CE
UniProt Gene Name
RHCE
UniProt Synonym Gene Names
RHC; RHE; RhPI
UniProt Entry Name
RHCE_HUMAN
NCBI Protein Information
blood group Rh(CE) polypeptide; blood group Rh(CE) polypeptide; RHCE blood group variant Crawford antigen Rh43; Rh blood group C antigen; Rh blood group antigen Evans; Rh polypeptide I; Rhesus blood group CE protein; Rhesus blood group E antigen; Rhesus blood group Rhce antigen; Rhesus system C and E polypeptides; blood group RhCcEe antigen; rh polypeptide 1; rhesus C/E antigens; rhesus blood group antigen, RhC antigen; rhesus blood group little e antigen; silenced Rh blood group CcEe antigen; truncated RHCE

NCBI Summary for CD240DCE

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD240DCE

RHCE: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. 14 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: integral to plasma membrane

Molecular Function: ammonium transmembrane transporter activity

Disease: Blood Group--rhesus System E Polypeptide
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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