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CD239 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS215430

Mouse anti Human CD239 antibody, clone BRIC221 recognizes human CD239, also known as Lutheran antigen or basal cell aghesion molecule.CD239 is a 597 amino acid, ~85kDa single pass type I membrane glycoprotein. Clone BRIC221 recognizes a monomorphic… More details

$245 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CD239, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD239
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
BRIC221
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
67,405 Da
OMIM
111200
3D Structure
ModBase 3D Structure for P50895
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD239 antibody
Immunohistology Frozen, ELISA (EIA), Flow cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)*
Application Notes for anti-CD239 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Western Blotting: Application Note: Non-reducing conditions required

Other Notes

Small volumes of anti-CD239 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD239 purchase

MBS215430 is an antibody targeting CD239. Also known as MOUSE ANTI HUMAN CD239. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD239. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
basal cell adhesion molecule isoform 2
NCBI Official Synonym Full Names
basal cell adhesion molecule (Lutheran blood group)
NCBI Official Symbol
BCAM
NCBI Official Synonym Symbols
AU; LU; CD239; MSK19
UniProt Protein Name
Basal cell adhesion molecule
UniProt Synonym Protein Names
Auberger B antigen; B-CAM cell surface glycoprotein; F8/G253 antigen; Lutheran antigen; Lutheran blood group glycoprotein; CD_antigen: CD239
UniProt Gene Name
BCAM
UniProt Synonym Gene Names
LU; MSK19
UniProt Entry Name
BCAM_HUMAN
NCBI Protein Information
basal cell adhesion molecule; Auberger b antigen; B-CAM cell surface glycoprotein; B-cell adhesion molecule; F8/G253 antigen; antigen identified by monoclonal antibody F8; basal cell adhesion molecule (Lu and Au blood groups); glycoprotein 95kDa

NCBI Summary for CD239

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
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UniProt Comments for CD239

Lu: Laminin alpha-5 receptor. May mediate intracellular signaling.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: transmembrane receptor activity; laminin receptor activity; laminin binding

Biological Process: cell-matrix adhesion; signal transduction; cell adhesion

Disease: Lutheran Null; Blood Group--lutheran System
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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