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Lymphotoxin BETA RECEPTOR (LTBR) Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS215692

Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on… More details

$1005 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LYMPHOTOXIN BETA RECEPTOR (Ltbr), Monoclonal Antibody
Full Product Name
RAT ANTI MOUSE LYMPHOTOXIN BETA RECEPTOR:Low Endotoxin
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
5G11b
Host
Rat
Form/Format
Low Endotoxin
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
44,956 Da
3D Structure
ModBase 3D Structure for P50284
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Recombinant extracellular domain of LT beta R
Fusion Partners||Spleen cells from immunised Wistar rats were fused with cells of the SP2/0 - Ag14 mouse myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Mouse
Applications Tested/Suitable for anti-Ltbr antibody
Flow cytometry (FC/FACS), Functional Assays (FN)
Application Notes for anti-Ltbr antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100

Testing Data of anti-Ltbr antibody

Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta (MBS215696)
Rat Anti-LTBR Monoclonal Antibody – Cat# MBS215692

Testing Data of anti-Ltbr antibody

Staining of mouse WEH1 cells with Rat anti Mouse lymphotoxin receptor beta : FITC (MBS215693)
Rat Anti-LTBR Monoclonal Antibody, Testing Data – Cat# MBS215692

Other Notes

Small volumes of anti-Ltbr antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ltbr purchase

MBS215692 is an antibody targeting Ltbr. Also known as RAT ANTI MOUSE LYMPHOTOXIN BETA RECEPTOR:Low Endotoxin. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for Ltbr. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 3
NCBI Official Synonym Full Names
lymphotoxin B receptor
NCBI Official Symbol
Ltbr
NCBI Official Synonym Symbols
CD18; Ltar; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 3
UniProt Synonym Protein Names
Lymphotoxin-beta receptor
UniProt Gene Name
Ltbr
UniProt Synonym Gene Names
Tnfcr; Tnfrsf3
UniProt Entry Name
TNR3_MOUSE
NCBI Protein Information
tumor necrosis factor receptor superfamily member 3; LT beta-R; LT-beta receptor; TNF receptor-related protein; lymphotoxin-beta receptor; tumor necrosis factor receptor superfamily, member 3

UniProt Comments for Ltbr

LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane

Molecular Function: identical protein binding; protein binding; ubiquitin protein ligase binding

Biological Process: apoptosis; positive regulation of JNK cascade; myeloid dendritic cell differentiation; lymph node development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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