CLASS II H-2i-Ab/S (MHC) Antibody – Mouse Monoclonal

Mouse anti MHC Class II H-2I-Ab/s antibody, clone OX-3 recognizes a polymorphic determinant of the rat RT1B MHC class II antigen, reacting with haplotypes u and l. The literature reports reactivity with Lewis, Wistar and AO strain rats but not BN, DA or PVG/c strains. Mouse anti MHC Class II H-2I-Ab/s antibody, clone OX-3 is useful for distinguishing RT1B positive cells from different rat strains, e.g. for recognising cells of donor origin in bone marrow reconstituted radiation chimaeras. Mouse anti MHC Class II H-2I-Ab/s antibody, clone OX-3 also cross reacts with mouse strains of the H-2 haplotypes b and s. Analysis of recombinant mouse strains has mapped the OX-3 determinant to the H-2I-A region. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region. In rats, this complex is referred to as the RT1 region. This product is routinely tested in flow cytometry on Lewis rat splenocytes.

Small volumes of anti-MHC CLASS II H-2I-Ab/s antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS216287 is an antibody targeting MHC CLASS II H-2I-Ab/s. Also known as MOUSE ANTI MHC CLASS II H-2I-Ab/s:FITC. Host: Mouse.