C-PEPTIDE I (INS1) Antibody – Mouse Monoclonal

Mouse anti Rat C-Peptide I antibody, clone 6H1 recognizes rat C-peptide I. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Mouse anti Rat C-Peptide I antibody, clone 6H1 recognizes rat C-peptide I and rat proinsulin. It does not recognize mouse C-peptide I and reacts very weakly with rat and mouse C-peptide II.

Small volumes of anti-Ins1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS216328 is an antibody targeting Ins1. Also known as MOUSE ANTI RAT C-PEPTIDE I. Host: Mouse.