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CD64 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS216579

Mouse anti Human CD64 antibody, clone 10.1 recognizes the human CD64 cell surface antigen, a 75kD glycoprotein expressed by monocytes. The antigen acts as a high affinity receptor for human IgG, and is also known as FcRI. Mouse anti Human CD64 antibody, clone… More details

$245 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD64, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD64
Product Gene Name
anti-CD64 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10.1
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
38,795 Da
OMIM
146760
3D Structure
ModBase 3D Structure for P12314
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Human monocytes
Fusion Partners||Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0-Ag14 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD64 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CD64 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100

Testing Data of anti-CD64 antibody

Staining of human peripheral blood monocytes with Mouse anti Human CD64:Alexa Fluor 647 (MBS219263A647)
Mouse Anti-CD64 Monoclonal Antibody – Cat# MBS216579

Testing Data of anti-CD64 antibody

Staining of peripheral blood monocytes with Mouse anti Human CD64 (MBS213146)
Mouse Anti-CD64 Monoclonal Antibody, Testing Data – Cat# MBS216579

Testing Data of anti-CD64 antibody

Staining of human peripheral blood monocytes with Mouse anti Human CD64 (MBS219263)
Mouse Anti-CD64 Monoclonal Antibody, Testing Data – Cat# MBS216579

Testing Data of anti-CD64 antibody

Staining of human peripheral blood monocytes with Mouse anti Human CD64:RPE (MBS213877)
Mouse Anti-CD64 Monoclonal Antibody, Testing Data – Cat# MBS216579

Testing Data of anti-CD64 antibody

Staining of human peripheral blood monocytes with Mouse anti Human CD64:FITC (MBS211091)
Mouse Anti-CD64 Monoclonal Antibody, Testing Data – Cat# MBS216579

Other Notes

Small volumes of anti-CD64 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD64 purchase

MBS216579 is an antibody targeting CD64. Also known as MOUSE ANTI HUMAN CD64. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD64. It may not necessarily be applicable to this product.

NCBI GI #
10835133
NCBI GeneID
2209
NCBI Accession #
NP_000557.1
UniProt Primary Accession #
P12314
UniProt Secondary Accession #
P12315; Q5QNW7; Q92495; Q92663
UniProt Related Accession #
P12314
GenBank Nucleotide #
NM_000566.3
NCBI Official Full Name
high affinity immunoglobulin gamma Fc receptor I
NCBI Official Synonym Full Names
Fc fragment of IgG, high affinity Ia, receptor (CD64)
NCBI Official Symbol
FCGR1A
NCBI Official Synonym Symbols
CD64; FCRI; CD64A; IGFR1
UniProt Protein Name
High affinity immunoglobulin gamma Fc receptor I
UniProt Synonym Protein Names
Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD_antigen: CD64
Protein Family
High affinity immunoglobulin gamma Fc receptor
UniProt Gene Name
FCGR1A
UniProt Synonym Gene Names
FCG1; FCGR1; IGFR1; IgG Fc receptor I; FcRI; FcgammaRIa
UniProt Entry Name
FCGR1_HUMAN
NCBI Protein Information
high affinity immunoglobulin gamma Fc receptor I; Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc gamma receptor; Fc-gamma RI; Fc-gamma receptor I A1; IgG Fc receptor I; fc-gamma RIA; fcgammaRIa

NCBI Summary for CD64

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

UniProt Comments for CD64

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q21.2-q21.3

Cellular Component: early endosome membrane; integral to membrane; plasma membrane

Molecular Function: protein binding; IgG binding; receptor signaling protein activity

Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; immune response; signal transduction; phagocytosis, engulfment
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Research Articles on CD64

1. An elevated neutrophil CD64 index is associated with both mucosal inflammation and an increased risk for clinical relapse in pediatric Crohn disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD64 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway antibodies  Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram

Diseases associated with anti-CD64 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >31 publications with CD64 and Inflammation
 Necrosis Antibodies  >15 publications with CD64 and Necrosis
 Respiratory Tract Diseases Antibodies  >9 publications with CD64 and Respiratory Tract Diseases
 Cardiovascular Diseases Antibodies  >8 publications with CD64 and Cardiovascular Diseases
 Lung Diseases Antibodies  >7 publications with CD64 and Lung Diseases
 Hematologic Diseases Antibodies  >5 publications with CD64 and Hematologic Diseases
 Asthma Antibodies  >4 publications with CD64 and Asthma
 Respiratory Hypersensitivity Antibodies  >3 publications with CD64 and Respiratory Hypersensitivity
 Atherosclerosis Antibodies  >3 publications with CD64 and Atherosclerosis
 Skin Neoplasms Antibodies  >3 publications with CD64 and Skin Neoplasms

Organs/Tissues associated with anti-CD64 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >79 publications with CD64 and Blood
 Lung Antibodies  >5 publications with CD64 and Lung
 Vascular Antibodies  >4 publications with CD64 and Vascular
 Kidney Antibodies  >3 publications with CD64 and Kidney
 Intestine Antibodies  >2 publications with CD64 and Intestine
 Stomach Antibodies  >1 publications with CD64 and Stomach
 Brain Antibodies  >1 publications with CD64 and Brain
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