Mouse Anti-LYVE1 Monoclonal Antibody – Cat# MBS831526

Western Blot analysis of LYVE1 antibody
A549 (lung carcinoma) cell lysate was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human LYVE-1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conj ugated to HRP and an ECL detection system.

LYVE1 Antibody – Mouse Monoclonal

Name: LYVE1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS831526
Price: 780 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS831526

MBS831526 is an antibody targeting LYVE1. Also known as LYVE1 antibody. Reactive in Human. Host: Mouse. Mouse monoclonal LYVE1 antibody More details

$780 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LYVE1, Monoclonal Antibody

Full Product Name

LYVE1 antibody

Product Gene Name

anti-LYVE1 antibody

Product Synonym Names

Monoclonal LYVE1; Anti-LYVE1; LYVE 1; extracellular link domain containing 1; XLkD1(extracellular link domain containing 1); LYVE-1; CRSBP-1; LYVE1; HAR; lymphatic vessel endothelial hyaluronan receptor 1

Clonality

Monoclonal

Isotype

IgG2b kappa

Clone Number

4G1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.

Purity/Purification

LYVE1 antibody was purified by protein-G affinity chromatography

Concentration

1 mg/ml (lot specific)

Specificity

Human

Preparation and Storage

Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Molecular Weight

35,213 Da

OMIM

605702

3D Structure

ModBase 3D Structure for Q9Y5Y7

Source Note

Anti-human LYVE-1 antibody, clone 4G1, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human LYVE-1 protein.

Cross-Reactivity

To be determined by end-user.

Immunogen

LYVE1 antibody was raised in mouse using recombinant human LYVE-1 (25-235 aa) purified from E Coli as the immunogen.

Product Categories/Family for anti-LYVE1 antibody

Cardiac Markers

Applications Tested/Suitable for anti-LYVE1 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-LYVE1 antibody

WB: 1:500-1:1,000

Other Notes

Small volumes of anti-LYVE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LYVE1. It may not necessarily be applicable to this product.

NCBI GI #

40549451

NCBI GeneID

10894

NCBI Accession #

NP_006682.2

UniProt Primary Accession #

Q9Y5Y7

UniProt Secondary Accession #

Q8TC18; Q9UNF4

UniProt Related Accession #

Q9Y5Y7

GenBank Nucleotide #

NM_006691.3

NCBI Official Full Name

lymphatic vessel endothelial hyaluronic acid receptor 1

NCBI Official Synonym Full Names

lymphatic vessel endothelial hyaluronan receptor 1

NCBI Official Symbol

LYVE1

NCBI Official Synonym Symbols

HAR; XLKD1; LYVE-1; CRSBP-1

UniProt Protein Name

Lymphatic vessel endothelial hyaluronic acid receptor 1

UniProt Synonym Protein Names

Cell surface retention sequence-binding protein 1; CRSBP-1; Extracellular link domain-containing protein 1; Hyaluronic acid receptor

Protein Family

Lymphatic vessel endothelial hyaluronic acid receptor

UniProt Gene Name

LYVE1

UniProt Synonym Gene Names

CRSBP1; HAR; XLKD1; LYVE-1; CRSBP-1

UniProt Entry Name

LYVE1_HUMAN

NCBI Protein Information

lymphatic vessel endothelial hyaluronic acid receptor 1

NCBI Summary for LYVE1

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

UniProt Comments for LYVE1

XLKD1: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity; hyaluronic acid binding; receptor activity

Biological Process: anatomical structure morphogenesis; glycosaminoglycan metabolic process; transport; cell-matrix adhesion; carbohydrate metabolic process; response to wounding; pathogenesis; signal transduction; cell motility; hyaluronan metabolic process; hyaluronan catabolic process

Research Articles on LYVE1

1. High LYVE expression is associated with visceral pleural invasion and lymphatic thromboembolism in non-small-cell lung cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LYVE1 antibody

Reference Product	PubMed Publications
CD44 antibody	>20 publications with LYVE1 and CD44
FGF2 antibody	>3 publications with LYVE1 and FGF2
STAB2 antibody	>3 publications with LYVE1 and STAB2
FIGF antibody	>1 publications with LYVE1 and FIGF
ATM antibody	>1 publications with LYVE1 and ATM

Pathways associated with anti-LYVE1 antibody

Products by Pathway	Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Hyaluronan Metabolism Pathway antibodies	Hyaluronan Metabolism Pathway Diagram
Hyaluronan Uptake And Degradation Pathway antibodies	Hyaluronan Uptake And Degradation Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-LYVE1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>22 publications with LYVE1 and Inflammation
Disease Models, Animal Antibodies	>14 publications with LYVE1 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>13 publications with LYVE1 and Neoplasms, Experimental
Lung Diseases Antibodies	>12 publications with LYVE1 and Lung Diseases
Necrosis Antibodies	>12 publications with LYVE1 and Necrosis
Liver Neoplasms Antibodies	>10 publications with LYVE1 and Liver Neoplasms
Edema Antibodies	>9 publications with LYVE1 and Edema
Liver Diseases Antibodies	>9 publications with LYVE1 and Liver Diseases
Uterine Cervical Neoplasms Antibodies	>7 publications with LYVE1 and Uterine Cervical Neoplasms
Fibrosis Antibodies	>5 publications with LYVE1 and Fibrosis

Organs/Tissues associated with anti-LYVE1 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>186 publications with LYVE1 and Vascular
Eye Antibodies	>23 publications with LYVE1 and Eye
Lung Antibodies	>22 publications with LYVE1 and Lung
Muscle Antibodies	>17 publications with LYVE1 and Muscle
Embryonic Tissue Antibodies	>16 publications with LYVE1 and Embryonic Tissue
Liver Antibodies	>15 publications with LYVE1 and Liver
Bone Antibodies	>11 publications with LYVE1 and Bone
Stomach Antibodies	>10 publications with LYVE1 and Stomach
Connective Tissue Antibodies	>9 publications with LYVE1 and Connective Tissue
Heart Antibodies	>7 publications with LYVE1 and Heart