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CD205 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS219678

Mouse anti Human CD205 antibody, clone HD30 specifically recognizes CD205, otherwise known as DEC205, a type I transmembrane glycoprotein and member of the macrophage mannose receptor family of C-type lectins, predominantly expressed by human dendritic cells.… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD205, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD205
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
HD30
Host
Mouse
Species Reactivity
Monkey
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
26,183 Da
OMIM
604524
3D Structure
ModBase 3D Structure for O60449
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Purified extracellular domain of human CD205-IgG1 Fc fusion protein.
Histology Positive Control Tissue||Human or monkey spleen and lymph node.
Fusion Partners||Spleen cells from immunised mice were fused with cells of the mouse SP2/0-Ag14 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD205 antibody
Immunohistology Frozen, Flow cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-CD205 antibody
Flow Cytometry: Use 10ul of suggested working dilution 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/200

Testing Data of anti-CD205 antibody

KM-H2 cells stained with Mouse anti Human CD205:RPE (MBS224500)
Mouse Anti-CD205 Monoclonal Antibody – Cat# MBS219678

Testing Data of anti-CD205 antibody

KM-H2 cells stained with Mouse anti Human CD205
Mouse Anti-CD205 Monoclonal Antibody, Testing Data – Cat# MBS219678

Other Notes

Small volumes of anti-CD205 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD205 purchase

MBS219678 is an antibody targeting CD205. Also known as MOUSE ANTI HUMAN CD205. Reactive in Monkey. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD205. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
GenBank Nucleotide #
NCBI Official Full Name
LY75-CD302 fusion protein isoform 1
NCBI Official Synonym Full Names
LY75-CD302 readthrough
NCBI Official Symbol
LY75-CD302
UniProt Protein Name
Lymphocyte antigen 75
UniProt Synonym Protein Names
C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD_antigen: CD205
Protein Family
UniProt Gene Name
LY75
UniProt Synonym Gene Names
CD205; CLEC13B; Ly-75
UniProt Entry Name
LY75_HUMAN
NCBI Protein Information
LY75-CD302 fusion protein; DEC-205/DCL-1 fusion

NCBI Summary for CD205

This locus represents naturally occurring read-through transcription between the neighboring lymphocyte antigen 75 (LY75) and CD302 molecule (CD302) genes. Alternative splicing results in multiple transcript variants encoding fusion products that share sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]
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UniProt Comments for CD205

LY75: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment. Causes reduced proliferation of B-lymphocytes. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q24

Cellular Component: integral to plasma membrane

Molecular Function: receptor activity; carbohydrate binding

Biological Process: endocytosis; immune response; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CD205 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with CD205 and Blood
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