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TALIN-2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS219815

Mouse anti Human Talin-2 antibody, clone 53.8 recognizes Talin-2, a high molecular weight skeletal protein involved in focal adhesion plaques. It plays a role in linking integrin to the actin cytoskeleton. It interacts with phosphatidylinositol-4-phosphate… More details

$440 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TALIN-2, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN TALIN-2
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
53.8
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
271,613 Da
OMIM
607349
3D Structure
ModBase 3D Structure for Q9Y4G6
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Histology Positive Control Tissue
Tonsil
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-TALIN-2 antibody
Immunofluorescence (IF)*, Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB)
Application Notes for anti-TALIN-2 antibody
Immunofluorescence: Application Note: Methanol treatment is required prior to antibody staining
Immunohistology - Paraffin: Minimum Dilution: 1/25; Maximum Dilution: 1/100

Other Notes

Small volumes of anti-TALIN-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TALIN-2 purchase

MBS219815 is an antibody targeting TALIN-2. Also known as MOUSE ANTI HUMAN TALIN-2. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TALIN-2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
talin-2
NCBI Official Synonym Full Names
talin 2
NCBI Official Symbol
TLN2
NCBI Official Synonym Symbols
ILWEQ
UniProt Protein Name
Talin-2
Protein Family
UniProt Gene Name
TLN2
UniProt Synonym Gene Names
KIAA0320
UniProt Entry Name
TLN2_HUMAN
NCBI Protein Information
talin-2

NCBI Summary for TALIN-2

This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]
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UniProt Comments for TALIN-2

talin 2: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: ruffle; focal adhesion; cytoplasm; plasma membrane; synapse; fascia adherens; intercellular junction; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; structural molecule activity; actin binding; insulin receptor binding

Biological Process: intercellular junction assembly; cytoskeletal anchoring; cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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