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CD39 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS219870

Mouse anti human CD39, clone A1 recognizes the human CD39 cell surface antigen, a ~70-100kDa molecule expressed on peripheral blood B cells, monocytes and T lymphocytes, and weakly by granulocytes. CD39 has intrinsic ecto-ATPase activity (Wang et al. 1996),… More details

$420 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD39, Monoclonal Antibody
Full Product Name
MOUSE ANTI HUMAN CD39
Product Gene Name
anti-CD39 antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
A1
Host
Mouse
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch
Molecular Weight
59,325 Da
OMIM
601752
3D Structure
ModBase 3D Structure for P49961
Perservative Stabilisers
0.09% Sodium Azide
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-CD39 antibody
Flow cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes for anti-CD39 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells

Testing Data of anti-CD39 antibody

Staining of human peripheral blood lymphocytes with Mouse anti Human CD39 followed by Rabbit F(ab')2 anti Mouse IgG:FITC (MBS235160)
Mouse Anti-CD39 Monoclonal Antibody – Cat# MBS219870

Testing Data of anti-CD39 antibody

Staining of human peripheral blood lymphocytes with Mouse anti Human CD39:FITC (MBS210642)
Mouse Anti-CD39 Monoclonal Antibody, Testing Data – Cat# MBS219870

Other Notes

Small volumes of anti-CD39 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD39 purchase

MBS219870 is an antibody targeting CD39. Also known as MOUSE ANTI HUMAN CD39. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD39. It may not necessarily be applicable to this product.

NCBI GI #
147905700
NCBI GeneID
953
NCBI Accession #
NP_001091645.1
UniProt Primary Accession #
P49961
UniProt Secondary Accession #
Q5T561; Q5T562; Q86VV3; Q9UQQ9; Q9Y3Q9; A9Z1X8; B4DWB9; B4E1X1; B7Z599; G3XAF6
UniProt Related Accession #
P49961
GenBank Nucleotide #
NM_001098175.1
NCBI Official Full Name
ectonucleoside triphosphate diphosphohydrolase 1 isoform 2
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 1
NCBI Official Symbol
ENTPD1
NCBI Official Synonym Symbols
CD39; SPG64; ATPDase; NTPDase-1
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 1
UniProt Synonym Protein Names
Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD_antigen: CD39
Protein Family
Ectonucleoside triphosphate diphosphohydrolase
UniProt Gene Name
ENTPD1
UniProt Synonym Gene Names
CD39; NTPDase 1; Ecto-ATPDase 1; Ecto-ATPase 1
UniProt Entry Name
ENTP1_HUMAN
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 1; CD39 antigen; NTPDase 1; ecto-ATP diphosphohydrolase 1; ecto-ATPDase 1; ecto-ATPase 1; ecto-apyrase; lymphoid cell activation antigen

NCBI Summary for CD39

The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

UniProt Comments for CD39

ENTPD1: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleotide Metabolism - purine; Membrane protein, multi-pass; EC 3.6.1.5; Extracellular matrix; Membrane protein, integral; Nucleotide Metabolism - pyrimidine; Hydrolase

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: membrane; integral to plasma membrane; plasma membrane; basal lamina

Molecular Function: protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: G-protein coupled receptor protein signaling pathway; platelet activation; purine ribonucleoside diphosphate catabolic process; blood coagulation; cell adhesion

Disease: Spastic Paraplegia 64, Autosomal Recessive
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Research Articles on CD39

1. Our data suggests that human bone marrow-derived mesenchymal stem cells can effectively suppress immune responses of the Th17 cells via the CD39-CD73-mediated adenosine-producing pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD39 antibody

 Reference Product  PubMed Publications
 NT5E antibody  >3 publications with CD39 and NT5E
 ENTPD6 antibody  >1 publications with CD39 and ENTPD6
 ENTPD5 antibody  >1 publications with CD39 and ENTPD5

Pathways associated with anti-CD39 antibody

 Products by Pathway  Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 UTP And CTP Dephosphorylation II Pathway antibodies  UTP And CTP Dephosphorylation II Pathway Diagram
 UTP And CTP Dephosphorylation II Pathway antibodies  UTP And CTP Dephosphorylation II Pathway Diagram

Diseases associated with anti-CD39 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >13 publications with CD39 and Inflammation
 Disease Models, Animal Antibodies  >8 publications with CD39 and Disease Models, Animal
 Necrosis Antibodies  >5 publications with CD39 and Necrosis
 Liver Diseases Antibodies  >3 publications with CD39 and Liver Diseases
 Kidney Diseases Antibodies  >3 publications with CD39 and Kidney Diseases
 Liver Neoplasms Antibodies  >3 publications with CD39 and Liver Neoplasms
 Nervous System Diseases Antibodies  >2 publications with CD39 and Nervous System Diseases
 Atherosclerosis Antibodies  >1 publications with CD39 and Atherosclerosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with CD39 and Carcinoma, Hepatocellular
 Hypertension Antibodies  >1 publications with CD39 and Hypertension

Organs/Tissues associated with anti-CD39 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >22 publications with CD39 and Blood
 Muscle Antibodies  >9 publications with CD39 and Muscle
 Liver Antibodies  >8 publications with CD39 and Liver
 Kidney Antibodies  >4 publications with CD39 and Kidney
 Heart Antibodies  >3 publications with CD39 and Heart
 Pancreas Antibodies  >3 publications with CD39 and Pancreas
 Bone Marrow Antibodies  >3 publications with CD39 and Bone Marrow
 Bone Antibodies  >3 publications with CD39 and Bone
 Embryonic Tissue Antibodies  >2 publications with CD39 and Embryonic Tissue
 Skin Antibodies  >2 publications with CD39 and Skin
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