CALCA Antibody – Goat Polyclonal

CALCA iso3: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; neuron projection; cell soma; cell; axon; cytoplasm; extracellular region; terminal button; intracellular; nucleus

Molecular Function: identical protein binding; neuropeptide hormone activity; calcitonin receptor binding; protein complex binding; receptor binding

Biological Process: negative regulation of osteoclast differentiation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of cell adhesion; positive regulation of interleukin-1 alpha production; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure; response to pain; positive regulation of vasodilation; protein amino acid phosphorylation; vasodilation; G-protein signaling, adenylate cyclase activating pathway; regulation of heart contraction; positive regulation of interleukin-8 production; monocyte chemotaxis; leukocyte adhesion; elevation of cytosolic calcium ion concentration; vasculature development; neuropeptide signaling pathway; receptor internalization; regulation of blood pressure; negative regulation of smooth muscle contraction; positive regulation of cAMP biosynthetic process; negative regulation of ossification; feeding behavior; negative regulation of blood pressure; positive regulation of adenylate cyclase activity; positive regulation of macrophage differentiation; detection of temperature stimulus involved in sensory perception of pain; inflammatory response; negative regulation of bone resorption; negative regulation of neurological process; neuromuscular junction development; aging; cytosolic calcium ion homeostasis; regulation of heart rate; adenylate cyclase activation; positive regulation of ossification; cellular calcium ion homeostasis; regulation of systemic arterial blood pressure by neurological process; G-protein coupled receptor internalization; response to heat; endothelial cell proliferation; activation of protein kinase activity; endothelial cell migration; negative regulation of transcription, DNA-dependent; embryo implantation