FGF 9 Antibody – Rabbit Polyclonal

FGF9: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3). Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Cellular Component: extracellular space; cell; cytoplasm; extracellular region; basement membrane; intracellular

Molecular Function: heparin binding; growth factor activity; receptor binding; fibroblast growth factor receptor binding

Biological Process: negative regulation of Wnt receptor signaling pathway; multicellular organismal development; embryonic skeletal development; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of activin receptor signaling pathway; positive regulation of MAPKKK cascade; cell-cell signaling; protein import into nucleus; male sex determination; positive regulation of cell proliferation; positive regulation of mesenchymal cell proliferation; chondrocyte differentiation; positive regulation of smoothened signaling pathway; angiogenesis; cell differentiation; embryonic gut development; regulation of timing of cell differentiation; positive regulation of cardiac muscle cell proliferation; embryonic limb morphogenesis; inner ear morphogenesis; fibroblast growth factor receptor signaling pathway; male gonad development; osteoblast differentiation; positive regulation of cell division; positive regulation of epithelial cell proliferation; lung development