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Il-13 (IL13) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS221264

Rabbit anti Mouse Interleukin-13 antibody recognizes mouse Interleukin-13 (IL-13), a 12.3kDa immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells and also by mast cells and NK cells. The biological properties of IL-13 include… More details

$740 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-13 (Il13), Polyclonal Antibody
Full Product Name
RABBIT ANTI MOUSE INTERLEUKIN-13
Product Gene Name
anti-Il13 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Purified
Purified IgG - lyophilised
Concentration
IgG concentration 1.0 mg/ml after reconstitution. (lot specific)
Preparation and Storage
Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Molecular Weight
14,108 Da
3D Structure
ModBase 3D Structure for P20109
Reconstitution
Reconstitute with 0.1ml distilled water Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Immunogen
Recombinant mouse IL-13
Buffer Solution||Phosphate buffered saline
Antiserum Preparation
Antisera to mouse IL-13 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Target Species
Mouse
Applications Tested/Suitable for anti-Il13 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-Il13 antibody
ELISA: Minimum Dilution: 0.5; Maximum Dilution: 2.0ug/ml;
Western Blotting: Minimum Dilution: 0.1; Maximum Dilution: 0.2ug/ml

Other Notes

Small volumes of anti-Il13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Il13 purchase

MBS221264 is an antibody targeting Il13. Also known as RABBIT ANTI MOUSE INTERLEUKIN-13. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Il13. It may not necessarily be applicable to this product.

NCBI GI #
6680403
NCBI GeneID
16163
NCBI Accession #
NP_032381.1
UniProt Primary Accession #
P20109
UniProt Related Accession #
P20109
GenBank Nucleotide #
NM_008355.3
NCBI Official Full Name
interleukin-13
NCBI Official Synonym Full Names
interleukin 13
NCBI Official Symbol
Il13
NCBI Official Synonym Symbols
Il-13
UniProt Protein Name
Interleukin-13
UniProt Synonym Protein Names
T-cell activation protein P600
Protein Family
Interleukin
UniProt Gene Name
Il13
UniProt Synonym Gene Names
Il-13; IL-13
UniProt Entry Name
IL13_MOUSE
NCBI Protein Information
interleukin-13; T-cell activation protein P600

UniProt Comments for Il13

IL13: Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH). Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. Belongs to the IL-4/IL-13 family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Cellular Component: extracellular space; cytoplasm; extracellular region; external side of plasma membrane

Molecular Function: interleukin-13 receptor binding; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity

Biological Process: response to nicotine; positive regulation of smooth muscle cell proliferation; microglial cell activation; regulation of proton transport; positive regulation of mast cell degranulation; positive regulation of connective tissue growth factor production; positive regulation of tyrosine phosphorylation of Stat6 protein; positive regulation of immunoglobulin production; positive regulation of protein secretion; positive regulation of B cell proliferation; immune response; positive regulation of ion transport; positive regulation of release of sequestered calcium ion into cytosol; inflammatory response; negative regulation of NAD(P)H oxidase activity; positive regulation of macrophage activation
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Research Articles on Il13

1. Report glyphosphate-rich air samples stimulate airway inflammation via IL-33/TSLP/IL-13 pathways.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Il13 antibody

 Reference Product  PubMed Publications
 Il4ra antibody  >878 publications with Il13 and Il4ra
 Stat6 antibody  >415 publications with Il13 and Stat6
 Il13ra1 antibody  >295 publications with Il13 and Il13ra1
 Il5 antibody  >116 publications with Il13 and Il5
 Muc5ac antibody  >76 publications with Il13 and Muc5ac
 Il2 antibody  >60 publications with Il13 and Il2
 Tslp antibody  >33 publications with Il13 and Tslp
 Il9 antibody  >27 publications with Il13 and Il9
 Csf2 antibody  >13 publications with Il13 and Csf2

Pathways associated with anti-Il13 antibody

 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response (BioCarta) Pathway antibodies  Cytokines And Inflammatory Response (BioCarta) Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram

Diseases associated with anti-Il13 antibody

 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >1406 publications with Il13 and Hypersensitivity
 Inflammation Antibodies  >1354 publications with Il13 and Inflammation
 Asthma Antibodies  >1297 publications with Il13 and Asthma
 Hypersensitivity, Immediate Antibodies  >1222 publications with Il13 and Hypersensitivity, Immediate
 Lung Diseases Antibodies  >1206 publications with Il13 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >1017 publications with Il13 and Respiratory Hypersensitivity
 Necrosis Antibodies  >642 publications with Il13 and Necrosis
 Fibrosis Antibodies  >337 publications with Il13 and Fibrosis
 Bronchial Hyperreactivity Antibodies  >233 publications with Il13 and Bronchial Hyperreactivity
 Dermatitis, Atopic Antibodies  >188 publications with Il13 and Dermatitis, Atopic

Organs/Tissues associated with anti-Il13 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2620 publications with Il13 and Blood
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