Goat Anti-CCL24 Polyclonal Antibody – Cat# MBS221335

EOTAXIN 2 (CCL24) Antibody – Goat Polyclonal

Name: CCL24 Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS221335
Price: 615 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS221335

Goat anti Human Eotaxin 2 antibody recognizes human Eotaxin 2, otherwise known as CCL24 and myeloid progenitor inhibitory factor 2 (MPIF-2), an eosinophil-specific chemokine which signals through the CCR3 receptor and is expressed principally by the jejunum… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

EOTAXIN 2 (CCL24), Polyclonal Antibody

Full Product Name

GOAT ANTI HUMAN EOTAXIN 2

Product Gene Name

anti-CCL24 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Form/Format

Purified
Purified IgG - lyophilised

Concentration

IgG concentration 1.0mg/ml (lot specific)

Preparation and Storage

Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.

Molecular Weight

13,134 Da

OMIM

602495

3D Structure

ModBase 3D Structure for O00175

Reconstitution

Reconstitute with 0.1ml distilled water.For long term storage the addition of 0.09% sodium azide is recommended.N.B. For functional studies do not add azide.

Immunogen

Recombinant human Eotaxin-2
Buffer Solution||Phosphate buffered saline

Antiserum Preparation

Antisera to human Eotaxin 2 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG prepared by affinity chromatography.

Target Species

Human

Applications Tested/Suitable for anti-CCL24 antibody

ELISA (EIA), Functional Assays (FN), Western Blot (WB)

Application Notes for anti-CCL24 antibody

ELISA: Maximum Dilution: 0.5ug/ml;
Functional Assays: Minimum Dilution: 4.0; Maximum Dilution: 6.0ug/ml;
Western Blotting: Minimum Dilution: 0.1; Maximum Dilution: 0.2ug/ml

Other Notes

Small volumes of anti-CCL24 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL24 purchase

MBS221335 is an antibody targeting CCL24. Also known as GOAT ANTI HUMAN EOTAXIN 2. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL24. It may not necessarily be applicable to this product.

NCBI GI #

22165427

NCBI GeneID

6369

NCBI Accession #

NP_002982.2

UniProt Primary Accession #

O00175

UniProt Secondary Accession #

B2R5K2

UniProt Related Accession #

O00175

GenBank Nucleotide #

NM_002991.2

NCBI Official Full Name

C-C motif chemokine 24

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 24

NCBI Official Symbol

CCL24

NCBI Official Synonym Symbols

Ckb-6; MPIF2; MPIF-2; SCYA24

UniProt Protein Name

C-C motif chemokine 24

UniProt Synonym Protein Names

CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; Myeloid progenitor inhibitory factor 2; MPIF-2; Small-inducible cytokine A24

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL24

UniProt Synonym Gene Names

MPIF2; SCYA24; MPIF-2

UniProt Entry Name

CCL24_HUMAN

NCBI Protein Information

C-C motif chemokine 24; CK-beta-6; eosinophil chemotactic protein 2; eotaxin-2; myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; small-inducible cytokine A24

NCBI Summary for CCL24

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008]

UniProt Comments for CCL24

CCL24: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: regulation of cell shape; positive regulation of angiogenesis; cell-cell signaling; positive regulation of actin filament polymerization; eosinophil chemotaxis; immune response; positive regulation of endothelial cell proliferation; cytoskeleton organization and biogenesis; chemotaxis; inflammatory response; signal transduction; positive regulation of cell migration; positive regulation of inflammatory response

Research Articles on CCL24

1. CCL11, CCL24, and CCL26 are increased in TB patients; hence, it seems that TB suppresses Th1 and the classic function of macrophages subsequently by inducing the chemokines' expression

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCL24 antibody

Reference Product	PubMed Publications
CCR3 antibody	>99 publications with CCL24 and CCR3
CCR5 antibody	>16 publications with CCL24 and CCR5
CCR2 antibody	>11 publications with CCL24 and CCR2
STAT6 antibody	>8 publications with CCL24 and STAT6
CCR1 antibody	>8 publications with CCL24 and CCR1
CXCR3 antibody	>7 publications with CCL24 and CXCR3
CCR8 antibody	>7 publications with CCL24 and CCR8
CXCR4 antibody	>6 publications with CCL24 and CXCR4
CXCR2 antibody	>2 publications with CCL24 and CXCR2
CXCR1 antibody	>1 publications with CCL24 and CXCR1

Pathways associated with anti-CCL24 antibody

Products by Pathway	Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with anti-CCL24 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>113 publications with CCL24 and Inflammation
Immune System Diseases Antibodies	>99 publications with CCL24 and Immune System Diseases
Hypersensitivity Antibodies	>93 publications with CCL24 and Hypersensitivity
Asthma Antibodies	>91 publications with CCL24 and Asthma
Respiratory Tract Diseases Antibodies	>90 publications with CCL24 and Respiratory Tract Diseases
Lung Diseases Antibodies	>83 publications with CCL24 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>65 publications with CCL24 and Respiratory Hypersensitivity
Necrosis Antibodies	>27 publications with CCL24 and Necrosis
Skin Diseases Antibodies	>24 publications with CCL24 and Skin Diseases
Dermatitis Antibodies	>18 publications with CCL24 and Dermatitis

Organs/Tissues associated with anti-CCL24 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>12 publications with CCL24 and Liver
Intestine Antibodies	>9 publications with CCL24 and Intestine
Spleen Antibodies	>8 publications with CCL24 and Spleen