GSK3 BETA Antibody – Rabbit Polyclonal

GSK3B: a proline-directed protein kinase of the GSK family. Phosphorylates and inactivates glycogen synthase. Participates in the Wnt signaling pathway. Involved in energy metabolism, neuronal cell development, and body pattern formation

Protein type: Protein kinase, CMGC; EC 2.7.11.1; EC 2.7.11.26; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CMGC group; GSK family; GSK subfamily

Cellular Component: centrosome; protein complex; dendritic spine; cytosol; beta-catenin destruction complex; ribonucleoprotein complex; lipid raft; nucleoplasm; growth cone; membrane; cell soma; perinuclear region of cytoplasm; cytoplasm; plasma membrane; dendritic shaft; nucleus

Molecular Function: p53 binding; beta-catenin binding; protein kinase binding; transcription factor binding; protein kinase activity; integrin binding; ionotropic glutamate receptor binding; protein serine/threonine kinase activity; NF-kappaB binding; protein binding; ubiquitin protein ligase binding; tau-protein kinase activity; kinase activity; tau protein binding; ATP binding

Biological Process: glycogen metabolic process; circadian rhythm; fat cell differentiation; negative regulation of MAP kinase activity; genetic imprinting; re-entry into mitotic cell cycle; positive regulation of protein binding; positive regulation of apoptosis; response to lithium ion; protein amino acid autophosphorylation; positive regulation of axon extension; establishment and/or maintenance of cell polarity; Wnt receptor signaling pathway through beta-catenin; protein amino acid phosphorylation; positive regulation of protein export from nucleus; protein export from nucleus; negative regulation of protein binding; positive regulation of cell-matrix adhesion; myoblast fusion; ER overload response; response to drug; regulation of microtubule-based process; cell migration; Wnt receptor signaling pathway; hippocampus development; myotube differentiation; negative regulation of dendrite morphogenesis; negative regulation of NFAT protein import into nucleus; positive regulation of peptidyl-serine phosphorylation; peptidyl-serine phosphorylation; negative regulation of neuron maturation; organ morphogenesis; positive regulation of protein complex assembly; axonogenesis; establishment of cell polarity; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; epithelial to mesenchymal transition; positive regulation of transcription from RNA polymerase II promoter; phosphorylation; negative regulation of protein complex assembly; negative regulation of apoptosis; regulation of neuronal synaptic plasticity