Rabbit Anti-CD290 Polyclonal Antibody – Cat# MBS221823

Western blot analysis of human lymph node lysate probed with Rabbit anti Human TLR10 (MBS221823) at 0.5(A) and 1(B) ug/ml

CD290 Antibody – Rabbit Polyclonal

Name: CD290 Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS221823
Price: 565 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS221823

Rabbit anti Human CD290 antibody recognizes human CD290, otherwise known as Toll-like receptor 10 (TLR10), a member of the Toll-like receptor family principally expressed in peripheral B lymphocytes and plasmacytoid dendritic cells. CD290 has been shown to… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CD290, Polyclonal Antibody

Full Product Name

RABBIT ANTI HUMAN CD290

Product Gene Name

anti-CD290 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

94,564 Da

OMIM

606270

3D Structure

ModBase 3D Structure for Q9BXR5

Perservative Stabilisers

0.02% Sodium Azide

Immunogen

Synthetic peptide corresponding to a 14 amino acid sequence within human CD290.
Buffer Solution||Phosphate buffered saline

Antiserum Preparation

Antisera to human CD290 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.

Target Species

Human

Applications Tested/Suitable for anti-CD290 antibody

Western Blot (WB)

Application Notes for anti-CD290 antibody

Western Blotting: Minimum Dilution: 0.5ug/ml; Maximum Dilution: 1.0ug/ml

Other Notes

Small volumes of anti-CD290 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD290 purchase

MBS221823 is an antibody targeting CD290. Also known as RABBIT ANTI HUMAN CD290. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD290. It may not necessarily be applicable to this product.

NCBI GI #

62865621

NCBI GeneID

81793

NCBI Accession #

NP_001017388.1

UniProt Primary Accession #

Q9BXR5

UniProt Secondary Accession #

Q32MI7; Q32MI8; Q5FWG4; Q6UXL3; A8K7L1; B3Y668; D1CS21; D1CS22

UniProt Related Accession #

Q9BXR5

GenBank Nucleotide #

NM_001017388.2

NCBI Official Full Name

toll-like receptor 10 isoform a

NCBI Official Synonym Full Names

toll-like receptor 10

NCBI Official Symbol

TLR10

NCBI Official Synonym Symbols

CD290

UniProt Protein Name

Toll-like receptor 10

UniProt Synonym Protein Names

CD_antigen: CD290

Protein Family

Toll-like receptor

UniProt Gene Name

TLR10

UniProt Entry Name

TLR10_HUMAN

NCBI Protein Information

toll-like receptor 10

NCBI Summary for CD290

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

UniProt Comments for CD290

TLR10: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Belongs to the Toll-like receptor family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 4p14

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: toll-like receptor 5 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; regulation of cytokine secretion; toll-like receptor signaling pathway; innate immune response; immune response; inflammatory response; positive regulation of inflammatory response; toll-like receptor 10 signaling pathway

Research Articles on CD290

1. Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD290 antibody

Reference Product	PubMed Publications
TLR1 antibody	>98 publications with CD290 and TLR1
TLR2 antibody	>78 publications with CD290 and TLR2
MYD88 antibody	>9 publications with CD290 and MYD88
FOXP3 antibody	>2 publications with CD290 and FOXP3

Pathways associated with anti-CD290 antibody

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
MyD88 Cascade Initiated On Plasma Membrane Pathway antibodies	MyD88 Cascade Initiated On Plasma Membrane Pathway Diagram
Toll Like Receptor 10 (TLR10) Cascade Pathway antibodies	Toll Like Receptor 10 (TLR10) Cascade Pathway Diagram
Toll Like Receptor 5 (TLR5) Cascade Pathway antibodies	Toll Like Receptor 5 (TLR5) Cascade Pathway Diagram
Toll-Like Receptors Cascades Pathway antibodies	Toll-Like Receptors Cascades Pathway Diagram

Diseases associated with anti-CD290 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>36 publications with CD290 and Inflammation
Disease Susceptibility Antibodies	>24 publications with CD290 and Disease Susceptibility
Asthma Antibodies	>11 publications with CD290 and Asthma
Lung Diseases Antibodies	>10 publications with CD290 and Lung Diseases
Hypersensitivity Antibodies	>9 publications with CD290 and Hypersensitivity
Respiratory Hypersensitivity Antibodies	>7 publications with CD290 and Respiratory Hypersensitivity
Necrosis Antibodies	>7 publications with CD290 and Necrosis
Carcinoma Antibodies	>5 publications with CD290 and Carcinoma
Kidney Diseases Antibodies	>4 publications with CD290 and Kidney Diseases
Cardiovascular Diseases Antibodies	>4 publications with CD290 and Cardiovascular Diseases

Organs/Tissues associated with anti-CD290 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>47 publications with CD290 and Blood
Lung Antibodies	>8 publications with CD290 and Lung
Spleen Antibodies	>7 publications with CD290 and Spleen
Bone Antibodies	>5 publications with CD290 and Bone
Lymph Node Antibodies	>5 publications with CD290 and Lymph Node
Intestine Antibodies	>4 publications with CD290 and Intestine
Brain Antibodies	>4 publications with CD290 and Brain
Connective Tissue Antibodies	>2 publications with CD290 and Connective Tissue
Trachea Antibodies	>1 publications with CD290 and Trachea