Goat Anti-ELMO1 Polyclonal Antibody – Cat# MBS221991

ELMO1 Antibody – Goat Polyclonal

Name: ELMO1 Antibody; Polyclonal; Goat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS221991
Price: 710 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS221991

MBS221991 is an antibody targeting ELMO1. Also known as GOAT ANTI HUMAN ELMO1. Reactive in Mouse (Expected from Sequence). Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

ELMO1, Polyclonal Antibody

Full Product Name

GOAT ANTI HUMAN ELMO1

Product Gene Name

anti-ELMO1 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Mouse (Expected from Sequence)

Form/Format

Purified
Ig fraction - liquid

Concentration

IgG concentration0.5mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

49,915 Da

OMIM

606420

3D Structure

ModBase 3D Structure for Q92556

Perservative Stabilisers

0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin

Immunogen

Peptide with the sequence PKEPSNYDFVYDCN from the C terminus of the protein. Sequence according to the Entrez Gene accession number NP_055615; NP_56979
Buffer Solution||Tris buffered saline

Target Species

Human

Applications Tested/Suitable for anti-ELMO1 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-ELMO1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELMO1. It may not necessarily be applicable to this product.

NCBI GI #

86788140

NCBI GeneID

9844

NCBI Accession #

NP_001034548.1

UniProt Primary Accession #

Q92556

UniProt Secondary Accession #

Q29R79; Q6ZTJ0; Q96PB0; Q9H0I1; A4D1X6

UniProt Related Accession #

Q92556

GenBank Nucleotide #

NM_001039459.2

NCBI Official Full Name

engulfment and cell motility protein 1 isoform 2

NCBI Official Synonym Full Names

engulfment and cell motility 1

NCBI Official Symbol

ELMO1

NCBI Official Synonym Symbols

CED12; CED-12; ELMO-1

UniProt Protein Name

Engulfment and cell motility protein 1

UniProt Synonym Protein Names

Protein ced-12 homolog

Protein Family

Engulfment and cell motility protein

UniProt Gene Name

ELMO1

UniProt Synonym Gene Names

KIAA0281

UniProt Entry Name

ELMO1_HUMAN

NCBI Protein Information

engulfment and cell motility protein 1; ced-12 homolog 1

NCBI Summary for ELMO1

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

UniProt Comments for ELMO1

ELMO1: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 7p14.1

Cellular Component: cytoskeleton; membrane; cytoplasm; plasma membrane; cytosol

Molecular Function: protein binding; SH3 domain binding

Biological Process: viral reproduction; apoptosis; innate immune response; Rac protein signal transduction; cell motility; vascular endothelial growth factor receptor signaling pathway; actin cytoskeleton organization and biogenesis; phagocytosis, engulfment; regulation of defense response to virus by virus

Research Articles on ELMO1

1. High ELMO1 expression is associated with serous ovarian cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ELMO1 antibody

Reference Product	PubMed Publications
RAC1 antibody	>36 publications with ELMO1 and RAC1
DOCK1 antibody	>32 publications with ELMO1 and DOCK1
RHOG antibody	>12 publications with ELMO1 and RHOG
SRC antibody	>9 publications with ELMO1 and SRC
CRK antibody	>9 publications with ELMO1 and CRK
RAC2 antibody	>3 publications with ELMO1 and RAC2
HCK antibody	>3 publications with ELMO1 and HCK

Pathways associated with anti-ELMO1 antibody

Products by Pathway	Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies	Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
Host Interactions Of HIV Factors Pathway antibodies	Host Interactions Of HIV Factors Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with anti-ELMO1 antibody

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>18 publications with ELMO1 and Kidney Diseases
Immune System Diseases Antibodies	>6 publications with ELMO1 and Immune System Diseases
Proteinuria Antibodies	>5 publications with ELMO1 and Proteinuria
Renal Insufficiency Antibodies	>5 publications with ELMO1 and Renal Insufficiency
Inflammation Antibodies	>3 publications with ELMO1 and Inflammation
Brain Diseases Antibodies	>2 publications with ELMO1 and Brain Diseases
Nervous System Diseases Antibodies	>2 publications with ELMO1 and Nervous System Diseases
Breast Neoplasms Antibodies	>2 publications with ELMO1 and Breast Neoplasms
Lung Neoplasms Antibodies	>1 publications with ELMO1 and Lung Neoplasms
Heart Diseases Antibodies	>1 publications with ELMO1 and Heart Diseases

Organs/Tissues associated with anti-ELMO1 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>14 publications with ELMO1 and Kidney
Blood Antibodies	>13 publications with ELMO1 and Blood
Brain Antibodies	>11 publications with ELMO1 and Brain
Testis Antibodies	>3 publications with ELMO1 and Testis
Muscle Antibodies	>2 publications with ELMO1 and Muscle
Lung Antibodies	>2 publications with ELMO1 and Lung
Thymus Antibodies	>2 publications with ELMO1 and Thymus
Embryonic Tissue Antibodies	>2 publications with ELMO1 and Embryonic Tissue
Bone Marrow Antibodies	>1 publications with ELMO1 and Bone Marrow
Mammary Gland Antibodies	>1 publications with ELMO1 and Mammary Gland