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Il-19 (IL19) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS222764

Rabbit anti Human Interleukin-19 antibody recognizes human IL-19 (interleukin-19), a 153 amino acid secreted helical cytokine belonging to the IL-10 family of regulatory cytokines, which is preferentially expressed in monocytes, but also expressed in B cells,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL-19 (IL19), Polyclonal Antibody
Full Product Name
RABBIT ANTI HUMAN INTERLEUKIN-19:Biotin
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Form/Format
Biotin
Purified IgG conjugated to Biotin - lyophilised
Concentration
IgG concentration 0.1mg/ml after reconstitution. (lot specific)
Preparation and Storage
Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Molecular Weight
23,079 Da
OMIM
605687
3D Structure
ModBase 3D Structure for Q9UHD0
Reconstitution
Reconstitute with 0.5ml sterile PBS containing 0.1% Bovine Serum Albumin. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Immunogen
Recombinant human IL-19
Buffer Solution||Phosphate buffered saline
Antiserum Preparation
Antisera to human IL-19 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Target Species
Human
Applications Tested/Suitable for anti-IL19 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-IL19 antibody
ELISA: Minimum Dilution: 0.25; Maximum Dilution: 1.0ug/ml;
Western Blotting: Minimum Dilution: 0.1; Maximum Dilution: 0.2ug/ml

Other Notes

Small volumes of anti-IL19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL19 purchase

MBS222764 is an antibody targeting IL19. Also known as RABBIT ANTI HUMAN INTERLEUKIN-19:Biotin. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL19. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-19 isoform 2
NCBI Official Synonym Full Names
interleukin 19
NCBI Official Symbol
IL19
NCBI Official Synonym Symbols
MDA1; NG.1; ZMDA1; IL-10C
UniProt Protein Name
Interleukin-19
UniProt Synonym Protein Names
Melanoma differentiation-associated protein-like protein; NG.1
Protein Family
UniProt Gene Name
IL19
UniProt Synonym Gene Names
ZMDA1; IL-19
UniProt Entry Name
IL19_HUMAN
NCBI Protein Information
interleukin-19; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein

NCBI Summary for IL19

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL19

IL19: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. Belongs to the IL-10 family.

Protein type: Secreted; Apoptosis; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 1q32.2

Cellular Component: extracellular space; extracellular region

Molecular Function: cytokine activity

Biological Process: apoptosis; positive regulation of JAK-STAT cascade; immune response; signal transduction; inflammatory response; interleukin-6 biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IL19 antibody

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