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ORAI3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3216394

This is a rabbit polyclonal antibody against ORAI3. It was validated on Western BlotTarget Description: ORAI3 is a key regulator or component of store-operated Ca2+ channel and transcription factor NFAT nuclear import. More details

$490 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ORAI3, Polyclonal Antibody
Full Product Name
ORAI3 Antibody - N-terminal region
Product Gene Name
Product Synonym Gene Name
MGC13024; TMEM142C
Immunogen Sequence
Synthetic peptide located within the following region: GDAGEQAPLN PEGESPAGSA TYREFVHRGY LDLMGASQHS LRALSWRRLY
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Tested:Human
Predicted: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purity/Purification
Affinity Purified
Concentration
Batch dependent within range: 100 ul at 0.5- 1mg/ml (lot specific)
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ORAI3 peptide (MBS3241294) is used for blocking the activity of ORAI3 antibody (MBS3216394)
Molecular Weight
31kDa
OMIM
610930
3D Structure
ModBase 3D Structure for Q9BRQ5
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 79%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ORAI3
Protein Size
295 amino acids
Protein Interactions
UBC
Blocking Peptide
For anti-ORAI3 (MBS3216394) antibody is MBS3241294.
Replacement Item
This anibody may replace item sc-292104 from Santa Cruz Biotechnology.
Applications Tested/Suitable for anti-ORAI3 antibody
Western Blot (WB)

Western Blot (WB) of anti-ORAI3 antibody

WB Suggested Anti-ORAI3 Antibody
Titration: 1.0 ug/ml
Positive Control: Placenta
Rabbit Anti-ORAI3 Polyclonal Antibody – Cat# MBS3216394

Other Notes

Small volumes of anti-ORAI3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ORAI3 purchase

MBS3216394 is an antibody targeting ORAI3. Also known as ORAI3 Antibody - N-terminal region. Reactive in Tested:Human
Predicted: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ORAI3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein orai-3
NCBI Official Synonym Full Names
ORAI calcium release-activated calcium modulator 3
NCBI Official Symbol
ORAI3
NCBI Official Synonym Symbols
TMEM142C
UniProt Protein Name
Protein orai-3
UniProt Synonym Protein Names
Transmembrane protein 142C
Protein Family
UniProt Gene Name
ORAI3
UniProt Synonym Gene Names
TMEM142C
UniProt Entry Name
ORAI3_HUMAN
NCBI Protein Information
protein orai-3

UniProt Comments for ORAI3

TMEM142C: Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import. Belongs to the Orai family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: integral to membrane

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ORAI3 antibody

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