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TGN46 Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS223180

Sheep anti Human TGN46 antibody recognizes a glycoprotein designated TGN46, that is localised primarily in the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network. TGN46 is a heavily glycosylated… More details

$1240 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TGN46, Polyclonal Antibody
Full Product Name
SHEEP ANTI HUMAN TGN46
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 0.25 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Molecular Weight
29,541 Da
OMIM
603062
3D Structure
ModBase 3D Structure for O43493
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
25% Glycerol
Immunogen
Recombinant human TGN46
Buffer Solution||Phosphate buffered saline
Antiserum Preparation
Antisera to human TGN46 were raised by repeated immunisation of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Target Species
Human
Applications Tested/Suitable for anti-TGN46 antibody
Immunohistology Frozen*, Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-TGN46 antibody
Immunohistology - Frozen: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml; Application Note: Fixation with 3% paraformaldehyde or methanol/acetone is recommended.
Western Blotting: Minimum Dilution: 0.1ug/ml; Maximum Dilution: 1ug/ml

Other Notes

Small volumes of anti-TGN46 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGN46 purchase

MBS223180 is an antibody targeting TGN46. Also known as SHEEP ANTI HUMAN TGN46. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for TGN46. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
trans-Golgi network integral membrane protein 2 isoform 2
NCBI Official Synonym Full Names
trans-golgi network protein 2
NCBI Official Symbol
TGOLN2
NCBI Official Synonym Symbols
TGN38; TGN46; TGN48; TGN51; TTGN2
UniProt Protein Name
Trans-Golgi network integral membrane protein 2
UniProt Synonym Protein Names
TGN38 homolog; TGN46; TGN48; Trans-Golgi network protein TGN51
UniProt Gene Name
TGOLN2
UniProt Synonym Gene Names
TGN46; TGN51
UniProt Entry Name
TGON2_HUMAN
NCBI Protein Information
trans-Golgi network integral membrane protein 2; TGN38 homolog; trans-Golgi network protein (46, 48, 51kD isoforms); trans-Golgi network protein TGN51

NCBI Summary for TGN46

This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for TGN46

TGOLN2: May be involved in regulating membrane traffic to and from trans-Golgi network. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: nucleoplasm; Golgi apparatus; transport vesicle; plasma membrane; integral to membrane; trans-Golgi network

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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