Goat Anti-CCR10 Polyclonal Antibody – Cat# MBS223513

Staining of paraffin embedded mouse small intestine with Goat anti mouse CCR10 (MBS223513)

CCR10 Antibody – Goat Polyclonal

Name: CCR10 Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS223513
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS223513

Goat anti Mouse CCR10 recognizes mouse CCR10 (C-C chemokine receptor type 10), otherwise known as GPR2, (G-protein coupled receptor 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, highly expressed in the small… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CCR10, Polyclonal Antibody

Full Product Name

GOAT ANTI MOUSE CCR10

Product Gene Name

anti-CCR10 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1.0 mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

38,900 Da

3D Structure

ModBase 3D Structure for Q9JL21

Perservative Stabilisers

0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin

Histology Positive Control Tissue

Mouse small intestine
Buffer Solution||Phosphate buffered saline

Antiserum Preparation

Antiserum to mouse CCR10 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Target Species

Mouse

Applications Tested/Suitable for anti-CCR10 antibody

ELISA (EIA), Flow cytometry (FC/FACS), Immunohistology Paraffin, Western Blot (WB)

Application Notes for anti-CCR10 antibody

ELISA: This product is suitable for use in indirect ELISA applications.
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
ELISA: Minimum Dilution: 1/100000
Immunohistology - Paraffin: Minimum Dilution: 1/250
Western Blotting: Minimum Dilution: 1/1000

Other Notes

Small volumes of anti-CCR10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCR10 purchase

MBS223513 is an antibody targeting CCR10. Also known as GOAT ANTI MOUSE CCR10. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR10. It may not necessarily be applicable to this product.

NCBI GI #

11024708

NCBI GeneID

12777

NCBI Accession #

NP_031747.2

UniProt Primary Accession #

Q9JL21

UniProt Secondary Accession #

Q542A4; Q9JIP1; Q9JL20

UniProt Related Accession #

Q9JL21

GenBank Nucleotide #

NM_007721.4

NCBI Official Full Name

C-C chemokine receptor type 10

NCBI Official Synonym Full Names

chemokine (C-C motif) receptor 10

NCBI Official Symbol

Ccr10

NCBI Official Synonym Symbols

Gpr2; Cmkbr9

UniProt Protein Name

C-C chemokine receptor type 10

UniProt Synonym Protein Names

Chemokine C-C receptor 9; G-protein coupled receptor 2

Protein Family

C-C chemokine receptor

UniProt Gene Name

Ccr10

UniProt Synonym Gene Names

Cmkbr9; Gpr2; C-C CKR-10; CC-CKR-10; CCR-10

UniProt Entry Name

CCR10_MOUSE

NCBI Protein Information

C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; G protein-coupled receptor 2; G-protein coupled receptor 2; chemokine C-C receptor 9

UniProt Comments for CCR10

CCR10: Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Cellular Component: cell surface; membrane; integral to plasma membrane; cell; plasma membrane; integral to membrane; cytosol

Molecular Function: G-protein coupled receptor activity; signal transducer activity; protein binding; C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; immune response; chemotaxis; signal transduction

Research Articles on CCR10

1. Our in vivo analysis demonstrated that uniform expression of Ccr10 on MSCs and alteration of Ccl27 level in the skin enhance extravasation of stem cells from circulation and facilitate their migration within cutaneous tissue

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CCR10 antibody

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with anti-CCR10 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>105 publications with CCR10 and Inflammation
Necrosis Antibodies	>23 publications with CCR10 and Necrosis
Colitis Antibodies	>7 publications with CCR10 and Colitis
Drug-Related Side Effects and Adverse Reactions Antibodies	>6 publications with CCR10 and Drug-Related Side Effects and Adverse Reactions
Sclerosis Antibodies	>4 publications with CCR10 and Sclerosis
Graft vs Host Disease Antibodies	>3 publications with CCR10 and Graft vs Host Disease
Heart Failure Antibodies	>2 publications with CCR10 and Heart Failure
Movement Disorders Antibodies	>2 publications with CCR10 and Movement Disorders
Poisoning Antibodies	>1 publications with CCR10 and Poisoning
Cardiomegaly Antibodies	>1 publications with CCR10 and Cardiomegaly

Organs/Tissues associated with anti-CCR10 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>167 publications with CCR10 and Blood
Skin Antibodies	>107 publications with CCR10 and Skin
Thymus Antibodies	>15 publications with CCR10 and Thymus