Goat Anti-CD193 Polyclonal Antibody – Cat# MBS223599

Staining of paraffin embedded mouse spleen with Goat anti Mouse CD193 (MBS223599)

CD193 Antibody – Goat Polyclonal

Name: CD193 Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS223599
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS223599

Goat anti Mouse CD193 antibody recognizes an epitope within the N-terminal (NT) region of mouse CD193, otherwise known as C-C chemokine receptor type 3 or CCR3. CD193 is a 359 amino acid ~42 kDa multi pass transmembrane glycoprotein and member of the… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CD193, Polyclonal Antibody

Full Product Name

GOAT ANTI MOUSE CD193 (N-TERMINAL)

Product Gene Name

anti-CD193 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Form/Format

Purified
Purified IgG - liquid

Concentration

IgG concentration 1.0 mg/ml (lot specific)

Preparation and Storage

Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Molecular Weight

41,783 Da

3D Structure

ModBase 3D Structure for P51678

Perservative Stabilisers

0.09% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin

Histology Positive Control Tissue

Spleen
Buffer Solution||Phosphate buffered saline

Antiserum Preparation

Antiserum to mouse CD193 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Target Species

Mouse

Applications Tested/Suitable for anti-CD193 antibody

Immunohistology Paraffin*, Western Blot (WB)

Application Notes for anti-CD193 antibody

Immunohistology - Paraffin: Minimum Dilution: 1/125; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Western Blotting: Minimum Dilution: 1/500

Other Notes

Small volumes of anti-CD193 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD193 purchase

MBS223599 is an antibody targeting CD193. Also known as GOAT ANTI MOUSE CD193 (N-TERMINAL). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD193. It may not necessarily be applicable to this product.

NCBI GI #

157012009

NCBI GeneID

12771

NCBI Accession #

NP_034044.3

UniProt Primary Accession #

P51678

UniProt Secondary Accession #

Q8K3M7

UniProt Related Accession #

P51678

GenBank Nucleotide #

NM_009914.4

NCBI Official Full Name

probable C-C chemokine receptor type 3

NCBI Official Synonym Full Names

chemokine (C-C motif) receptor 3

NCBI Official Symbol

Ccr3

NCBI Official Synonym Symbols

CKR3; Cmkbr3; CC-CKR3; Cmkbr1l2

UniProt Protein Name

Probable C-C chemokine receptor type 3

UniProt Synonym Protein Names

Macrophage inflammatory protein 1-alpha receptor-like 2; MIP-1 alpha RL2; CD_antigen: CD193

Protein Family

C-C chemokine receptor

UniProt Gene Name

Ccr3

UniProt Synonym Gene Names

Cmkbr1l2; Cmkbr3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3; MIP-1 alpha RL2

UniProt Entry Name

CCR3_MOUSE

NCBI Protein Information

probable C-C chemokine receptor type 3; C-C CKR-3; CC chemokine receptor 3; CC-CKR-3; CCR-3; MIP-1 alpha RL2; MIP-1 alphaRL2; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; macrophage inflammatory protein 1-alpha receptor-like 2

UniProt Comments for CD193

CCR3: Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, cytokine; Motility/polarity/chemotaxis; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Cellular Component: extracellular space; membrane; plasma membrane; integral to membrane; endosome

Molecular Function: G-protein coupled receptor activity; protein binding; signal transducer activity; C-C chemokine receptor activity; chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of angiogenesis; mast cell chemotaxis; eosinophil chemotaxis; positive regulation of endothelial cell proliferation; inflammatory response; signal transduction; chemotaxis

Research Articles on CD193

1. The RNA interference therapy to CCR3 by local administration pernasal can suppress the process of the development, migration and invasion of the allergic rhinitis eosinophil.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD193 antibody

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with anti-CD193 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>366 publications with CD193 and Inflammation
Asthma Antibodies	>247 publications with CD193 and Asthma
Lung Diseases Antibodies	>201 publications with CD193 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>175 publications with CD193 and Respiratory Hypersensitivity
HIV Infections Antibodies	>123 publications with CD193 and HIV Infections
Necrosis Antibodies	>82 publications with CD193 and Necrosis
Dermatitis, Atopic Antibodies	>43 publications with CD193 and Dermatitis, Atopic
Gastrointestinal Diseases Antibodies	>39 publications with CD193 and Gastrointestinal Diseases
Cardiovascular Diseases Antibodies	>32 publications with CD193 and Cardiovascular Diseases
Arthritis, Rheumatoid Antibodies	>27 publications with CD193 and Arthritis, Rheumatoid

Organs/Tissues associated with anti-CD193 antibody

Organ/Tissue Name	Pubmed Publications
Other Antibodies	>298 publications with CD193 and Other
Bone Marrow Antibodies	>89 publications with CD193 and Bone Marrow
Spleen Antibodies	>47 publications with CD193 and Spleen
Mixed Antibodies	>18 publications with CD193 and Mixed