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EMR1 Antibody – Hamster Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224415

Hamster anti Human EMR1 antibody, clone A10 recognizes human EMR1 (EGF-like module containing, mucin-like, hormone receptor-like 1). EMR1 is a seven-span transmembrane protein which is a member of the EGF-TM7 family of receptors. EMR1 is the human ortholog of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EMR1, Monoclonal Antibody
Full Product Name
HAMSTER ANTI HUMAN EMR1:RPE
Product Gene Name
Clonality
Monoclonal
Isotype
IgG
Clone Number
A10
Host
Hamster
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Molecular Weight
82,771 Da
OMIM
600493
3D Structure
ModBase 3D Structure for Q14246
Reconstitution
Reconstitute with 1.0ml distilled water
Perservative Stabilisers||0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation||Purified IgG prepared by affinity chromatography on Protein G
Immunogen
Fibroblast cell line ARH102 expressing CD97-EMR1 (EGF1-6)
Fusion Partners||Spleen cells from immunised Armenian hamster were fused with cells of the mouse SP2/0 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Human
Applications Tested/Suitable for anti-EMR1 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-EMR1 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat

Testing Data #1 of anti-EMR1 antibody

Human eosinophils stained with Hamster anti Human EMR1 (MBS224708) followed by Goat anti Hamster IgG:Biotin (MBS235098) and Streptavidin:RPE (MBS238414)
Hamster Anti-EMR1 Monoclonal Antibody – Cat# MBS224415

Testing Data #2 of anti-EMR1 antibody

Human eosinophils stained with Hamster anti Human EMR1:RPE (MBS224415)
Hamster Anti-EMR1 Monoclonal Antibody, Testing Data #2 – Cat# MBS224415

Other Notes

Small volumes of anti-EMR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EMR1 purchase

MBS224415 is an antibody targeting EMR1. Also known as HAMSTER ANTI HUMAN EMR1:RPE. Host: Hamster.

Additional Details

NCBI/Uniprot data below describe general gene information for EMR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
EGF-like module-containing mucin-like hormone receptor-like 1 isoform 2
NCBI Official Synonym Full Names
egf-like module containing, mucin-like, hormone receptor-like 1
NCBI Official Symbol
EMR1
NCBI Official Synonym Symbols
TM7LN3
UniProt Protein Name
EGF-like module-containing mucin-like hormone receptor-like 1
UniProt Synonym Protein Names
EGF-like module receptor 1; EMR1 hormone receptor
UniProt Gene Name
EMR1
UniProt Synonym Gene Names
TM7LN3
UniProt Entry Name
EMR1_HUMAN
NCBI Protein Information
EGF-like module-containing mucin-like hormone receptor-like 1; EGF-like module receptor 1; EMR1 hormone receptor; egf-like module containing, mucin-like, hormone receptor-like sequence 1

NCBI Summary for EMR1

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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UniProt Comments for EMR1

EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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