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CLEC2 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224416

Rat anti Mouse CLEC2 antibody, clone 17D9 recognizes mouse C-type lectin domain family 1 member B, also known as CLEC2 or CLEC1B. CLEC2 acts as a receptor for rhodocytin, a platelet-aggregating protein found in snake venom. CLEC2 expression is not restricted… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLEC2, Monoclonal Antibody
Full Product Name
RAT ANTI MOUSE CLEC2:RPE
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
17D9
Host
Rat
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Preparation and Storage
Prior to reconstitution store at 4 degree C. After reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Molecular Weight
22,870 Da
3D Structure
ModBase 3D Structure for Q9JL99
Reconstitution
Reconstitute with 1ml distilled water
Perservative Stabilisers||0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
5% Glycerol
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
RBL-2H3 cells stably expressing HA-tagged mouse CLEC2.
Fusion Partners||Spleen cells from immunised Wistar rats were fused with cells of the rat Y3 myeloma cell line.
Buffer Solution||Phosphate buffered saline
Target Species
Mouse
Applications Tested/Suitable for anti-CLEC2 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-CLEC2 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat

Testing Data #1 of anti-CLEC2 antibody

Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:FITC (MBS224383)
Rat Anti-CLEC2 Monoclonal Antibody – Cat# MBS224416

Testing Data #2 of anti-CLEC2 antibody

Mouse peripheral blood platelets stained with Rat anti Mouse CLEC-2:RPE (MBS224416)
Rat Anti-CLEC2 Monoclonal Antibody, Testing Data #2 – Cat# MBS224416

Other Notes

Small volumes of anti-CLEC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLEC2 purchase

MBS224416 is an antibody targeting CLEC2. Also known as RAT ANTI MOUSE CLEC2:RPE. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CLEC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-type lectin domain family 1 member B isoform 2
NCBI Official Synonym Full Names
C-type lectin domain family 1, member b
NCBI Official Symbol
Clec1b
NCBI Official Synonym Symbols
Clec2; Clec-2; 1810061I13Rik
UniProt Protein Name
C-type lectin domain family 1 member B
UniProt Synonym Protein Names
C-type lectin-like receptor 2; CLEC-2
UniProt Gene Name
Clec1b
UniProt Synonym Gene Names
Clec2; CLEC-2
UniProt Entry Name
CLC1B_MOUSE
NCBI Protein Information
C-type lectin domain family 1 member B; C-type lectin-like receptor 2

UniProt Comments for CLEC2

CLEC1B: Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; integral to plasma membrane; integral to membrane

Molecular Function: transmembrane receptor activity; carbohydrate binding

Biological Process: cell surface receptor linked signal transduction; platelet formation; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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