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TREM-1 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224418

Rat anti Mouse Trem-1 antibody, clone L5-B8.2A12.3A12 recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TREM-1, Monoclonal Antibody
Full Product Name
RAT ANTI MOUSE TREM-1:RPE
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
L5-B8.2A12.3A12
Host
Rat
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of reconstitution.
Molecular Weight
25,409 Da
3D Structure
ModBase 3D Structure for Q9JKE2
Reconstitution
Reconstitute with 1.0ml distilled water
Perservative Stabilisers||0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen
Mouse TREM-1 Fc fusion protein
Buffer Solution||Phosphate buffered saline
Target Species
Mouse
Applications Tested/Suitable for anti-TREM-1 antibody
Flow cytometry (FC/FACS)
Application Notes for anti-TREM-1 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat

Testing Data #1 of anti-TREM-1 antibody

Staining of J774 cells with Rat anti Mouse TREM-1:Alexa FluorR -647 (MBS219711)
Rat Anti-TREM-1 Monoclonal Antibody – Cat# MBS224418

Testing Data #2 of anti-TREM-1 antibody

Staining of J774 cells with Rat anti Mouse TREM-1:Alexa FluorR 488 (MBS219711)
Rat Anti-TREM-1 Monoclonal Antibody, Testing Data #2 – Cat# MBS224418

Testing Data #3 of anti-TREM-1 antibody

Staining of J774 cells with Rat anti Mouse TREM-1:RPE (MBS224418)
Rat Anti-TREM-1 Monoclonal Antibody, Testing Data #3 – Cat# MBS224418

Other Notes

Small volumes of anti-TREM-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TREM-1 purchase

MBS224418 is an antibody targeting TREM-1. Also known as RAT ANTI MOUSE TREM-1:RPE. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for TREM-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
triggering receptor expressed on myeloid cells 1
NCBI Official Synonym Full Names
triggering receptor expressed on myeloid cells 1
NCBI Official Symbol
Trem1
UniProt Protein Name
Triggering receptor expressed on myeloid cells 1
UniProt Synonym Protein Names
CD_antigen: CD354
UniProt Gene Name
Trem1
UniProt Synonym Gene Names
TREM-1
UniProt Entry Name
TREM1_MOUSE
NCBI Protein Information
triggering receptor expressed on myeloid cells 1; triggering receptor expressed in monocytes 1

UniProt Comments for TREM-1

TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: membrane; cell; integral to membrane

Biological Process: neutrophil chemotaxis; cell migration; cytokine metabolic process; cytokine secretion during immune response; chemokine metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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