• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ENTPD1/CD39 Recombinant Antibody – CHO Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9247119

MBS9247119 is a recombinant antibody targeting ENTPD1/CD39. Also known as Anti-ENTPD1/CD39 Reference Antibody (TTX-030). Reactive in Human. Host: CHO Cell. More details

$510 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ENTPD1/CD39, Recombinant Antibody
Full Product Name
Anti-ENTPD1/CD39 Reference Antibody (TTX-030)
Product Gene Name
ENTPD1/CD39 recombinant antibody
Clonality
Monoclonal
Isotype
IgG4
Host
CHO Cell
Species Reactivity
Human
Form/Format
Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Concentration
1mg/ml (lot specific)
Specificity
ENTPD1/CD39
Preparation and Storage
Store at -80 degree C for 2 years under sterile conditions; -20 degree C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
Molecular Weight
57,965 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (97471536..97637023). Location: 10q24
OMIM
601752
3D Structure
ModBase 3D Structure for P49961
Endotoxin
< 0.001EU/ug, determined by LAL method.
Conjugation
Unconjugated
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product Categories/Family for ENTPD1/CD39 recombinant antibody

Primary Antibodies
Applications Tested/Suitable for ENTPD1/CD39 recombinant antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Kinetics, Functional Assay (FUNC), Animal Model

SDS-Page of ENTPD1/CD39 recombinant antibody

Anti-ENTPD1 / CD39 Reference Antibody (TTX-030) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%
CHO Anti-ENTPD1/CD39 Monoclonal Recombinant Antibody – Cat# MBS9247119

Testing Data of ENTPD1/CD39 recombinant antibody

The purity of Anti-ENTPD1 / CD39 Reference Antibody (TTX-030)is more than 99.83% ,determined by SEC-HPLC.
CHO Anti-ENTPD1/CD39 Monoclonal Recombinant Antibody, Testing Data – Cat# MBS9247119

Testing Data of ENTPD1/CD39 recombinant antibody

TTX-030 inhibited the tumor growth of MOLP-8 on NCG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 99.3% at 20 mpk at D25.
CHO Anti-ENTPD1/CD39 Monoclonal Recombinant Antibody, Testing Data – Cat# MBS9247119

Other Notes

Small volumes of ENTPD1/CD39 recombinant antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ENTPD1/CD39. It may not necessarily be applicable to this product.

NCBI GI #
147905700
NCBI GeneID
953
NCBI Accession #
NP_001091645.1
UniProt Primary Accession #
P49961
UniProt Secondary Accession #
Q5T561; Q5T562; Q86VV3; Q9UQQ9; Q9Y3Q9; A9Z1X8; B4DWB9; B4E1X1; B7Z599; G3XAF6
UniProt Related Accession #
P49961
GenBank Nucleotide #
NM_001098175.1
NCBI Official Full Name
ectonucleoside triphosphate diphosphohydrolase 1 isoform 2
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 1
NCBI Official Symbol
ENTPD1
NCBI Official Synonym Symbols
CD39; ATPDase; NTPDase-1
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 1
UniProt Synonym Protein Names
Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen
UniProt Gene Name
ENTPD1
UniProt Synonym Gene Names
CD39; NTPDase 1; Ecto-ATPDase 1
UniProt Entry Name
ENTP1_HUMAN
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; CD39 antigen; ecto-apyrase; ecto-ATPase 1; ecto-ATPDase 1; ecto-ATP diphosphohydrolase 1; lymphoid cell activation antigen

NCBI Summary for ENTPD1/CD39

The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

UniProt Comments for ENTPD1/CD39

ENTPD1: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; EC 3.6.1.5; Extracellular matrix; Nucleotide Metabolism - pyrimidine; Membrane protein, multi-pass; Hydrolase

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: membrane; integral to plasma membrane; plasma membrane; basal lamina

Molecular Function: protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: platelet activation; G-protein coupled receptor protein signaling pathway; purine ribonucleoside diphosphate catabolic process; cell adhesion; blood coagulation

Disease: Spastic Paraplegia 64, Autosomal Recessive
Show more

Research Articles on ENTPD1/CD39

1. hCD39 expressed by circulating leukocytes and intrinsic renal cells limits innate AN injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ENTPD1/CD39 recombinant antibody

 Products by Pathway  Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 UTP And CTP Dephosphorylation II Pathway antibodies  UTP And CTP Dephosphorylation II Pathway Diagram

Diseases associated with ENTPD1/CD39 recombinant antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >8 publications with ENTPD1/CD39 and Disease Models, Animal
 Inflammation Antibodies  >7 publications with ENTPD1/CD39 and Inflammation
 Neoplasms Antibodies  >6 publications with ENTPD1/CD39 and Neoplasms
 Necrosis Antibodies  >4 publications with ENTPD1/CD39 and Necrosis
 Kidney Diseases Antibodies  >3 publications with ENTPD1/CD39 and Kidney Diseases
 Liver Diseases Antibodies  >3 publications with ENTPD1/CD39 and Liver Diseases
 Ischemia Antibodies  >3 publications with ENTPD1/CD39 and Ischemia
 Nervous System Diseases Antibodies  >2 publications with ENTPD1/CD39 and Nervous System Diseases
 Atherosclerosis Antibodies  >1 publications with ENTPD1/CD39 and Atherosclerosis
 Hypertension Antibodies  >1 publications with ENTPD1/CD39 and Hypertension

Organs/Tissues associated with ENTPD1/CD39 recombinant antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >2 publications with ENTPD1/CD39 and Heart
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000