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CD16 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224814

Rat anti Mouse CD16 anitbody, clone AT154-2, recognizes CD16, also known as FcRIII. CD16 is a low affiniity activatory receptor which interacts preferentially with mouse IgG1, IgG2a and IgG2b immune complexes and is involved in various effector functions… More details

$510 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD16, Monoclonal Antibody
Full Product Name
RAT ANTI MOUSE CD16: FITC
Product Gene Name
anti-CD16 antibody
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
AT154-2
Host
Rat
Species Reactivity
Mouse
Form/Format
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Concentration
IgG concentration 0.1 mg/ml (lot specific)
Specificity
CD16
Preparation and Storage
Store at +4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch
Molecular Weight
30,036 Da
3D Structure
ModBase 3D Structure for P08508
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preservative Stabilisers
0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin
Buffer Solution
Phosphate buffered saline
Applications Tested/Suitable for anti-CD16 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD16 antibody
Flow Cytometry: 1/10

Other Notes

Small volumes of anti-CD16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD16 purchase

MBS224814 is an antibody targeting CD16. Also known as RAT ANTI MOUSE CD16: FITC. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD16. It may not necessarily be applicable to this product.

NCBI GI #
119877
NCBI GeneID
14131
NCBI Accession #
P08508.1
UniProt Primary Accession #
P08508
UniProt Related Accession #
P08508
NCBI Official Full Name
Low affinity immunoglobulin gamma Fc region receptor III
NCBI Official Synonym Full Names
Fc receptor, IgG, low affinity III
NCBI Official Symbol
Fcgr3
NCBI Official Synonym Symbols
CD16
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor III
UniProt Synonym Protein Names
Fc-gamma RIII; FcRIII; CD_antigen: CD16
Protein Family
CD160 antigen
UniProt Gene Name
Fcgr3
UniProt Synonym Gene Names
IgG Fc receptor III; FcRIII
UniProt Entry Name
FCGR3_MOUSE
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor III

UniProt Comments for CD16

FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells.

Protein type: Receptor, misc.; Membrane protein, integral; Cell surface

Cellular Component: external side of plasma membrane; integral to membrane; membrane; plasma membrane

Molecular Function: IgG binding; IgG receptor activity

Biological Process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; mast cell activation; neutrophil chemotaxis; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of type I hypersensitivity; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; regulation of immune response; serotonin secretion
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Research Articles on CD16

1. Nlrp3-inflammasome and FcgammaRIII have roles in Dengue virus and antiplatelet autoantibody-induced hemorrhage

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD16 antibody

 Reference Product  PubMed Publications
 Fcgr2b antibody  >338 publications with CD16 and Fcgr2b
 Syk antibody  >304 publications with CD16 and Syk
 Lyn antibody  >101 publications with CD16 and Lyn
 Fcgr1 antibody  >94 publications with CD16 and Fcgr1
 Vav1 antibody  >23 publications with CD16 and Vav1
 Hck antibody  >23 publications with CD16 and Hck
 Fgr antibody  >10 publications with CD16 and Fgr
 Fcer1g antibody  >4 publications with CD16 and Fcer1g
 Plcg2 antibody  >1 publications with CD16 and Plcg2

Pathways associated with anti-CD16 antibody

 Products by Pathway  Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Leishmaniasis Pathway antibodies  Leishmaniasis Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies  Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram

Organs/Tissues associated with anti-CD16 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >11921 publications with CD16 and Blood
 Spleen Antibodies  >963 publications with CD16 and Spleen
 Bone Antibodies  >889 publications with CD16 and Bone
 Bone Marrow Antibodies  >764 publications with CD16 and Bone Marrow
 Brain Antibodies  >682 publications with CD16 and Brain
 Kidney Antibodies  >676 publications with CD16 and Kidney
 Lung Antibodies  >635 publications with CD16 and Lung
 Liver Antibodies  >608 publications with CD16 and Liver
 Muscle Antibodies  >494 publications with CD16 and Muscle
 Skin Antibodies  >492 publications with CD16 and Skin
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