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Peroxiredoxin 2 (PRDX2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224831

Mouse anti peroxiredoxin 2 antibody, clone 1E8, recognizes peroxiredoxin 2 also known as natural killer cell-enhancing factor B, thiol-specific antioxidant protein and thioredoxin peroxidase 1. Peroxiredoxin 2 is a cytoplasmic enzyme involved in cellular… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PEROXIREDOXIN 2 (PRDX2), Monoclonal Antibody
Full Product Name
MOUSE ANTI PEROXIREDOXIN 2
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1E8
Host
Mouse
Species Reactivity
Human
Form/Format
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Specificity
PEROXIREDOXIN 2
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch
Molecular Weight
15,819 Da
OMIM
600538
3D Structure
ModBase 3D Structure for P32119
Reactivity Notes
Mouse, Rat
Preparation
IgG fraction prepared by ammonium sulphate precipitation
Preservative Stabilisers
0.03% Sodium Azide (NaN3), 0.01% Bovine Serum Albumin, 50% Glycerol
Buffer Solution
HEPES buffered saline
Applications Tested/Suitable for anti-PRDX2 antibody
ELISA, Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-PRDX2 antibody
Western Blot: 1/2000; 1/4000

Testing Data of anti-PRDX2 antibody

Mouse anti peroxiredoxin 2 antibody IHC staining of human cancerous endometrial tissue (formalin fixed, paraffin embedded)
Mouse Anti-PRDX2 Monoclonal Antibody – Cat# MBS224831

Testing Data of anti-PRDX2 antibody

Mouse anti peroxiredoxin 2 antibody IHC staining of normal human endometrial tissue (formalin fixed, paraffin embedded)
Mouse Anti-PRDX2 Monoclonal Antibody, Testing Data – Cat# MBS224831

Testing Data of anti-PRDX2 antibody

Mouse anti peroxiredoxin 2 antibody IHC staining of normal human kidney tissue (formalin fixed, paraffin embedded)
Mouse Anti-PRDX2 Monoclonal Antibody, Testing Data – Cat# MBS224831

Testing Data of anti-PRDX2 antibody

Mouse anti peroxiredoxin 2 antibody recognizes a band of approximately 26 kDa in HeLa (lane 1), 293T (lane 2), SH-SY5Y (lane 3) and HepG2 (lane 4) cell lysates
Mouse Anti-PRDX2 Monoclonal Antibody, Testing Data – Cat# MBS224831

Other Notes

Small volumes of anti-PRDX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRDX2 purchase

MBS224831 is an antibody targeting PRDX2. Also known as MOUSE ANTI PEROXIREDOXIN 2. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PRDX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Peroxiredoxin-2
NCBI Official Synonym Full Names
peroxiredoxin 2
NCBI Official Symbol
PRDX2
NCBI Official Synonym Symbols
PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
UniProt Protein Name
Peroxiredoxin-2
UniProt Synonym Protein Names
Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
Protein Family
UniProt Gene Name
PRDX2
UniProt Synonym Gene Names
NKEFB; TDPX1; NKEF-B; TSA
UniProt Entry Name
PRDX2_HUMAN
NCBI Protein Information
peroxiredoxin-2

NCBI Summary for PRDX2

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
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UniProt Comments for PRDX2

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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