Rabbit Anti-CD268/BAFF-R Polyclonal Antibody – Cat# MBS224864

Western blot analysis of rat kidney tissue lysate probed with Rabbit anti CD268 / BAFF-R antibody

CD268/BAFF-R Antibody – Rabbit Polyclonal

Name: CD268/BAFF-R Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS224864
Price: 465 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224864

Rabbit anti CD268 / BAFF-R antibody recognizes the CD268 antigen, also known as BAFF-R (B cell activating factor belonging to the TNF family receptor) and TNFRSF13C (tumor necrosis factor receptor superfamily member 13C). CD268 / BAFF-R is a B-cell receptor… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CD268/BAFF-R, Polyclonal Antibody

Full Product Name

RABBIT ANTI CD268 / BAFF-R

Product Gene Name

anti-CD268/BAFF-R antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Purified IgG - liquid

Concentration

IgG concentration 0.5 mg/ml (lot specific)

Specificity

CD268 / BAFF-R

Preparation and Storage

Store at -20 degree C Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch

Molecular Weight

17,576 Da

3D Structure

ModBase 3D Structure for Q9D8D0

Reactivity Notes

Human, Rat

Preservative Stabilisers

30% Glycerol, 0.5% Bovine Serum Albumin, 0.01% Thiomersal

Buffer Solution

Phosphate buffered saline

Applications Tested/Suitable for anti-CD268/BAFF-R antibody

Western Blot (WB)

Application Notes for anti-CD268/BAFF-R antibody

Western Blot: 0.5; 4.0 ug/ml

Other Notes

Small volumes of anti-CD268/BAFF-R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD268/BAFF-R purchase

MBS224864 is an antibody targeting CD268/BAFF-R. Also known as RABBIT ANTI CD268 / BAFF-R. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD268/BAFF-R. It may not necessarily be applicable to this product.

NCBI GI #

21264095

NCBI GeneID

72049

NCBI Accession #

Q9D8D0.1

UniProt Primary Accession #

Q9D8D0

UniProt Related Accession #

Q9D8D0

NCBI Official Full Name

Tumor necrosis factor receptor superfamily member 13C

NCBI Official Synonym Full Names

tumor necrosis factor receptor superfamily, member 13c

NCBI Official Symbol

Tnfrsf13c

NCBI Official Synonym Symbols

Bcmd; Baffr; Bcmd1; BAFF-R; Bcmd-1; Lvis22; 2010006P15Rik

UniProt Protein Name

Tumor necrosis factor receptor superfamily member 13C

UniProt Synonym Protein Names

B-cell maturation defect; B-cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD_antigen: CD268

UniProt Gene Name

Tnfrsf13c

UniProt Synonym Gene Names

Baffr; Bcmd; Br3; BAFF-R

UniProt Entry Name

TR13C_MOUSE

NCBI Protein Information

tumor necrosis factor receptor superfamily member 13C

UniProt Comments for CD268/BAFF-R

BAFF-R: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4); also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.; Cell cycle regulation; Cell surface

Cellular Component: external side of plasma membrane; integral to membrane; membrane

Biological Process: adaptive immune response; B cell costimulation; B cell homeostasis; immune system process; positive regulation of B cell proliferation; positive regulation of germinal center formation; positive regulation of interferon-gamma biosynthetic process; positive regulation of T cell proliferation; regulation of immune response; T cell costimulation

Research Articles on CD268/BAFF-R

1. Heteromers consisting of one BAFF and two APRIL bind to receptor TACI, BCMA but not to BAFFR.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD268/BAFF-R antibody

Reference Product	PubMed Publications
Tnfsf13b antibody	>137 publications with CD268/BAFF-R and Tnfsf13b
Bcr antibody	>26 publications with CD268/BAFF-R and Bcr
Traf3 antibody	>8 publications with CD268/BAFF-R and Traf3
Traf2 antibody	>4 publications with CD268/BAFF-R and Traf2
Btk antibody	>3 publications with CD268/BAFF-R and Btk
Rel antibody	>3 publications with CD268/BAFF-R and Rel
Cxcr5 antibody	>1 publications with CD268/BAFF-R and Cxcr5
Cd22 antibody	>1 publications with CD268/BAFF-R and Cd22

Pathways associated with anti-CD268/BAFF-R antibody

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Intestinal Immune Network For IgA Production Pathway antibodies	Intestinal Immune Network For IgA Production Pathway Diagram
Intestinal Immune Network For IgA Production Pathway antibodies	Intestinal Immune Network For IgA Production Pathway Diagram
NF-kappa B Signaling Pathway antibodies	NF-kappa B Signaling Pathway Diagram
Primary Immunodeficiency Pathway antibodies	Primary Immunodeficiency Pathway Diagram

Diseases associated with anti-CD268/BAFF-R antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>144 publications with CD268/BAFF-R and Necrosis
Immune System Diseases Antibodies	>114 publications with CD268/BAFF-R and Immune System Diseases
Inflammation Antibodies	>25 publications with CD268/BAFF-R and Inflammation
Common Variable Immunodeficiency Antibodies	>13 publications with CD268/BAFF-R and Common Variable Immunodeficiency
Disease Models, Animal Antibodies	>12 publications with CD268/BAFF-R and Disease Models, Animal
Kidney Diseases Antibodies	>8 publications with CD268/BAFF-R and Kidney Diseases
Hyperplasia Antibodies	>6 publications with CD268/BAFF-R and Hyperplasia
Hypertrophy Antibodies	>5 publications with CD268/BAFF-R and Hypertrophy
Demyelinating Diseases Antibodies	>4 publications with CD268/BAFF-R and Demyelinating Diseases
Atherosclerosis Antibodies	>4 publications with CD268/BAFF-R and Atherosclerosis

Organs/Tissues associated with anti-CD268/BAFF-R antibody

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>36 publications with CD268/BAFF-R and Spleen
Bone Marrow Antibodies	>21 publications with CD268/BAFF-R and Bone Marrow
Mixed Antibodies	>3 publications with CD268/BAFF-R and Mixed
Embryonic Tissue Antibodies	>2 publications with CD268/BAFF-R and Embryonic Tissue
Intestine Antibodies	>1 publications with CD268/BAFF-R and Intestine