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HEAT SHOCK PROTEIN 90 ALPHA (HSP90AA1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224928

Rabbit anti heat shock protein 90 alpha antibody recognizes heat shock protein 90 alpha, also known as lipopolysaccharide-associated protein 2, renal carcinoma antigen NY-REN-38 and HSP86. Heat shock protein 90 alpha is a highly abundant protein. It acts as a… More details

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Product Overview

Product Name
HEAT SHOCK PROTEIN 90 ALPHA (HSP90AA1), Polyclonal Antibody
Full Product Name
RABBIT ANTI HEAT SHOCK PROTEIN 90 ALPHA
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Purified IgG - liquid
Concentration
IgG concentration 0.5 mg/ml (lot specific)
Specificity
HEAT SHOCK PROTEIN 90 ALPHA
Preparation and Storage
Store at -20 degree C Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch
Molecular Weight
98,161 Da
OMIM
140571
3D Structure
ModBase 3D Structure for P07900
Reactivity Notes
Mouse, Rat
Preservative Stabilisers
30% Glycerol, 0.5% Bovine Serum Albumin, 0.01% Thiomersal
Buffer Solution
Phosphate buffered saline
Applications Tested/Suitable for anti-HSP90AA1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-HSP90AA1 antibody
Immunohistochemistry- Paraffin: 5 ug/ml
Western Blot: 0.5; 4.0 ug/ml

Western Blot (WB) of anti-HSP90AA1 antibody

Western blot analysis of Jurkat cell lysate (lane 1) and mouse small intestine tissue lysate (lane 2) probed with Rabbit anti heat shock protein 90 alpha antibody
Rabbit Anti-HSP90AA1 Polyclonal Antibody – Cat# MBS224928

Other Notes

Small volumes of anti-HSP90AA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSP90AA1 purchase

MBS224928 is an antibody targeting HSP90AA1. Also known as RABBIT ANTI HEAT SHOCK PROTEIN 90 ALPHA. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSP90AA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Heat shock protein HSP 90-alpha
NCBI Official Synonym Full Names
heat shock protein 90kDa alpha family class A member 1
NCBI Official Symbol
HSP90AA1
NCBI Official Synonym Symbols
EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HEL-S-65p
UniProt Protein Name
Heat shock protein HSP 90-alpha
UniProt Synonym Protein Names
Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38
Protein Family
UniProt Gene Name
HSP90AA1
UniProt Synonym Gene Names
HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2
UniProt Entry Name
HS90A_HUMAN
NCBI Protein Information
heat shock protein HSP 90-alpha

NCBI Summary for HSP90AA1

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
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UniProt Comments for HSP90AA1

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (PubMed:11274138, PubMed:11276205, PubMed:15577939, PubMed:15937123, PubMed:27353360).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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