Rabbit Anti-PAK6 Polyclonal Antibody – Cat# MBS224943

Western blot analysis of Jurkat cell lysate (lane 1 & 2) probed with Rabbit anti PAK6 antibody

PAK6 Antibody – Rabbit Polyclonal

Name: PAK6 Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS224943
Price: 465 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS224943

Rabbit anti PAK6 antibody recognizes a region around amino acid 552 of mouse PAK6. It is a member of the family of serine/threonine p21-activated kinases and plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PAK6, Polyclonal Antibody

Full Product Name

RABBIT ANTI PAK6

Product Gene Name

anti-PAK6 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Purified IgG - liquid

Concentration

IgG concentration 0.5 mg/ml (lot specific)

Specificity

PAK6

Preparation and Storage

Store at -20 degree C Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch

Molecular Weight

74,867 Da

3D Structure

ModBase 3D Structure for Q3ULB5

Reactivity Notes

Horse, Human, Pig, Rat

Preservative Stabilisers

30% Glycerol, 0.5% Bovine Serum Albumin, 0.01% Thiomersal

Buffer Solution

Phosphate buffered saline

Applications Tested/Suitable for anti-PAK6 antibody

Western Blot (WB)

Application Notes for anti-PAK6 antibody

Western Blot: 0.5; 4.0 ug/ml

Other Notes

Small volumes of anti-PAK6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAK6 purchase

MBS224943 is an antibody targeting PAK6. Also known as RABBIT ANTI PAK6. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PAK6. It may not necessarily be applicable to this product.

NCBI GI #

123794718

NCBI GeneID

214230

NCBI Accession #

Q3ULB5.1

UniProt Primary Accession #

Q3ULB5

UniProt Secondary Accession #

Q3TY26

UniProt Related Accession #

Q3ULB5

NCBI Official Full Name

Serine/threonine-protein kinase PAK 6

NCBI Official Synonym Full Names

p21 protein (Cdc42/Rac)-activated kinase 6

NCBI Official Symbol

Pak6

NCBI Official Synonym Symbols

4732456M09

UniProt Protein Name

Serine/threonine-protein kinase PAK 6

UniProt Synonym Protein Names

p21-activated kinase 6; PAK-6

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

Pak6

UniProt Synonym Gene Names

PAK-6

UniProt Entry Name

PAK6_MOUSE

NCBI Protein Information

serine/threonine-protein kinase PAK 6

UniProt Comments for PAK6

PAK6: a protein kinase of the STE20 family. Interacts with androgen receptor (AR), and cotranslocates into the nucleus with AR in response to androgen. Highly expressed in testis and prostate tissues.

Protein type: Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Nuclear receptor co-regulator; EC 2.7.11.1; Kinase, protein; STE group; STE20 family; PAKB subfamily

Cellular Component: cytoplasm; nucleus

Molecular Function: ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; Rac GTPase binding; transferase activity

Biological Process: actin cytoskeleton organization and biogenesis; activation of protein kinase activity; cell migration; learning; locomotory behavior; memory; phosphorylation; protein amino acid phosphorylation; regulation of apoptosis; regulation of MAPKKK cascade; regulation of mitotic cell cycle; regulation of transcription, DNA-dependent; Rho protein signal transduction; stress-activated protein kinase signaling pathway

Research Articles on PAK6

1. data suggest that PAK-6 p21-activated kinase plays a role in weight gain unrelated to exercise and caloric intake

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PAK6 antibody

Reference Product	PubMed Publications
Cdc42 antibody	>16 publications with PAK6 and Cdc42
Rac1 antibody	>5 publications with PAK6 and Rac1
Limk1 antibody	>1 publications with PAK6 and Limk1
Raf1 antibody	>1 publications with PAK6 and Raf1
Arhgef7 antibody	>1 publications with PAK6 and Arhgef7
Rac2 antibody	>1 publications with PAK6 and Rac2

Pathways associated with anti-PAK6 antibody

Products by Pathway	Pathway Diagram
Androgen Receptor Signaling Pathway antibodies	Androgen Receptor Signaling Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
ErbB Signaling Pathway antibodies	ErbB Signaling Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Integrin-mediated Cell Adhesion Pathway antibodies	Integrin-mediated Cell Adhesion Pathway Diagram
Ras Signaling Pathway antibodies	Ras Signaling Pathway Diagram

Diseases associated with anti-PAK6 antibody

Disease Name	Pubmed Publications
Prostatic Neoplasms Antibodies	>14 publications with PAK6 and Prostatic Neoplasms
Liver Neoplasms Antibodies	>3 publications with PAK6 and Liver Neoplasms
Cell Transformation, Neoplastic Antibodies	>3 publications with PAK6 and Cell Transformation, Neoplastic
Liver Diseases Antibodies	>3 publications with PAK6 and Liver Diseases
Neoplasm Metastasis Antibodies	>3 publications with PAK6 and Neoplasm Metastasis
Carcinoma, Hepatocellular Antibodies	>3 publications with PAK6 and Carcinoma, Hepatocellular
Neoplasms, Experimental Antibodies	>2 publications with PAK6 and Neoplasms, Experimental
Memory Disorders Antibodies	>1 publications with PAK6 and Memory Disorders
Cognition Disorders Antibodies	>1 publications with PAK6 and Cognition Disorders
Learning Disorders Antibodies	>1 publications with PAK6 and Learning Disorders

Organs/Tissues associated with anti-PAK6 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>8 publications with PAK6 and Brain
Kidney Antibodies	>2 publications with PAK6 and Kidney
Spinal Cord Antibodies	>1 publications with PAK6 and Spinal Cord
Skin Antibodies	>1 publications with PAK6 and Skin
Embryonic Tissue Antibodies	>1 publications with PAK6 and Embryonic Tissue