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GDF9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225112

Rabbit anti GDF9 antibody recognizes human GDF9, also known as growth/differentiation factor 9. GDF9 belongs to the transforming growth factor (TGF) beta superfamily. GDF9 is an oocyte derived growth factor with a role in ovarian folliculogenesis. More details

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Technical Datasheet View PDF
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Product Overview

Product Name
GDF9, Polyclonal Antibody
Full Product Name
Rabbit anti GDF9
Product Gene Name
Product Synonym Names
GDF9 Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse (Expected from Sequence), Rat (Expected from Sequence)
Form/Format
Liquid in phosphate buffered saline with 0.02% sodium azide, 50% glycerol.
Purity/Purification
Purified whole serum by affinity chromatography.
Preparation and Storage
Store at -20 degree C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch
Molecular Weight
51,444 Da
OMIM
601918
3D Structure
ModBase 3D Structure for O60383
Immunogen
Recombinant human GDF9
Preperation
Antiserum to GDF9 was raised by repeated immunization of rabbits with highly purified antigen.
Applications Tested/Suitable for anti-GDF9 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-GDF9 antibody
IHC-Paraffin: 1:50-1:100
WB: 1:500-1:1000

Western Blot (WB) of anti-GDF9 antibody

Western blot analysis of SW626 cell lysate using Rabbit anti GDF9 antibody
Rabbit Anti-GDF9 Polyclonal Antibody – Cat# MBS225112

Immunohistochemistry (IHC) of anti-GDF9 antibody

Immunohistochemistry of paraffin-embedded human stomach cancer tissue using Rabbit anti GDF9 antibody
Rabbit Anti-GDF9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS225112

Other Notes

Small volumes of anti-GDF9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDF9 purchase

MBS225112 is an antibody targeting GDF9. Also known as Rabbit anti GDF9. Reactive in Human, Mouse (Expected from Sequence), Rat (Expected from Sequence). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GDF9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Growth/differentiation factor 9
NCBI Official Synonym Full Names
growth differentiation factor 9
NCBI Official Symbol
GDF9
UniProt Protein Name
Growth/differentiation factor 9
UniProt Gene Name
GDF9
UniProt Synonym Gene Names
GDF-9
NCBI Protein Information
growth/differentiation factor 9

NCBI Summary for GDF9

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Reduced expression of this gene may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins. [provided by RefSeq, Jul 2016]
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UniProt Comments for GDF9

Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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