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C-Jun (JUN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225217

Rabbit anti c-Jun (pThr239) antibody recognizes proto-oncogene c-Jun, also known as V-jun avian sarcoma virus 17 oncogene homolog and p39, when phosphorylated at threonine 239.c-Jun is a member of the Jun family of transcription factors and is a subunit of… More details

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Product Overview

Product Name
c-Jun, Polyclonal Antibody
Full Product Name
Rabbit anti c-Jun (pThr239)
Product Gene Name
Product Synonym Names
c-Jun (pThr239) Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid in phosphate buffered saline with 0.02% sodium azide, 50% glycerol.
Purity/Purification
Purified whole serum by affinity chromatography.
Preparation and Storage
Store at -20 degree C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch
Molecular Weight
35,676 Da
OMIM
165160
3D Structure
ModBase 3D Structure for P05412
Immunogen
Phospho specific-peptide corresponding to residues surrounding threonine 239 of human c-Jun
Preperation
Antiserum to c-Jun (pThr239) was raised by repeated immunization of rabbits with highly purified antigen.
Applications Tested/Suitable for anti-JUN antibody
Western Blot (WB)
Application Notes for anti-JUN antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-JUN antibody

Western blot analysis of extracts from HeLa cells untreated or treated with UV (for 15-30 minutes) using Rabbit anti c-Jun (pThr239) antibody
Rabbit Anti-JUN Polyclonal Antibody – Cat# MBS225217

Other Notes

Small volumes of anti-JUN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JUN purchase

MBS225217 is an antibody targeting JUN. Also known as Rabbit anti c-Jun (pThr239). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for JUN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Transcription factor AP-1
NCBI Official Synonym Full Names
Jun proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol
JUN
NCBI Official Synonym Symbols
AP1; p39; AP-1; c-Jun
UniProt Protein Name
Transcription factor AP-1
UniProt Synonym Protein Names
Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39
Protein Family
UniProt Gene Name
JUN
UniProt Synonym Gene Names
AP1
NCBI Protein Information
transcription factor AP-1

NCBI Summary for JUN

This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
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UniProt Comments for JUN

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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