Mouse Anti-KIF2C Monoclonal Antibody – Cat# MBS225520

Western blot analysis of whole cell lysates probed with kinesin family member 2C antibody followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000) and visualized on the ChemiDoc MP with 42 second exposure. Arrow points to kinesin family member 2C (molecular weight 81 kDa)

Kinesin Family Member 2c (KIF2C) Antibody – Mouse Monoclonal

Name: KIF2C Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS225520
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225520

MBS225520 is an antibody targeting KIF2C. Also known as Kinesin Family Member 2C Antibody with Control Lysate. Reactive in Human. Host: Mouse. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Kinesin Family Member 2C (KIF2C), Monoclonal Antibody

Full Product Name

Kinesin Family Member 2C Antibody with Control Lysate

Product Gene Name

anti-KIF2C antibody

Product Synonym Names

Mouse anti KINESIN FAMILY MEMBER 2C; Kinesin Family Member 2C Antibody

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CPTC20

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid in phosphate buffered saline with 0.09% sodium azide (NaN3).

Purity/Purification

Purified by affinity chromatography on Protein G from tissue culture supernatant

Preparation and Storage

Antibody: Store undiluted at -20 degree C, avoiding repeated freeze thaw cycles.
Lysate: Store lyophilized lysate at -20 degree C.
After reconstitution aliquot and store at -20 degree C for up to 3 months or at -80 degree C for longer term storage. Shelf Life: As supplied, 12 months from date of despatch.

Molecular Weight

81 kDa

OMIM

604538

3D Structure

ModBase 3D Structure for Q99661

Immunogen

Recombinant protein of human kinesin family member 2C

Lysate Composition

400ug Jurkat lysate lyophilized in RIPA buffer

Lysate Reconstitution

If using DDT reconstitute the lyophilized lysate with 190mul DI H2O, add 200mul 2x Laemmli Sample Buffer and 10mul 2M DTT.
If using BME reconstitute the lyophilized lysate with 180mul DI H2O, add 200mul 2x Laemmli Sample Buffer and 20u

Applications Tested/Suitable for anti-KIF2C antibody

Western Blot (WB)

Application Notes for anti-KIF2C antibody

WB: 1:1000
Western Blotting: Detects a band of approximately 81 kDa in Jurkat cell lysates.

Other Notes

Small volumes of anti-KIF2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF2C. It may not necessarily be applicable to this product.

NCBI GI #

20141607

NCBI GeneID

11004

NCBI Accession #

Q99661.2

UniProt Primary Accession #

Q99661

UniProt Secondary Accession #

Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q9BWV8; B3ITR9

UniProt Related Accession #

Q99661

NCBI Official Full Name

Kinesin-like protein KIF2C

NCBI Official Synonym Full Names

kinesin family member 2C

NCBI Official Symbol

KIF2C

NCBI Official Synonym Symbols

MCAK; CT139; KNSL6

UniProt Protein Name

Kinesin-like protein KIF2C

UniProt Synonym Protein Names

Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK

Protein Family

Kinesin-like protein

UniProt Gene Name

KIF2C

UniProt Synonym Gene Names

KNSL6; MCAK

NCBI Protein Information

kinesin-like protein KIF2C

NCBI Summary for KIF2C

This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

UniProt Comments for KIF2C

In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108).

Research Articles on KIF2C

1. KIF-2C expression in tumor tissues may serve as an independent prognostic marker for male, but not female, patients with operable esophageal squamous cell carcinomas.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KIF2C antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Aurora B Signaling Pathway antibodies	Aurora B Signaling Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Kinesins Pathway antibodies	Kinesins Pathway Diagram
M Phase Pathway antibodies	M Phase Pathway Diagram
MHC Class II Antigen Presentation Pathway antibodies	MHC Class II Antigen Presentation Pathway Diagram

Diseases associated with anti-KIF2C antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>5 publications with KIF2C and Breast Neoplasms
Cell Transformation, Neoplastic Antibodies	>4 publications with KIF2C and Cell Transformation, Neoplastic
Neoplasms, Experimental Antibodies	>3 publications with KIF2C and Neoplasms, Experimental
Nervous System Diseases Antibodies	>2 publications with KIF2C and Nervous System Diseases
Lung Diseases Antibodies	>2 publications with KIF2C and Lung Diseases
Adenocarcinoma Antibodies	>2 publications with KIF2C and Adenocarcinoma
Lung Neoplasms Antibodies	>2 publications with KIF2C and Lung Neoplasms
Ovarian Neoplasms Antibodies	>1 publications with KIF2C and Ovarian Neoplasms
Infertility, Male Antibodies	>1 publications with KIF2C and Infertility, Male
Atherosclerosis Antibodies	>1 publications with KIF2C and Atherosclerosis

Organs/Tissues associated with anti-KIF2C antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>9 publications with KIF2C and Blood
Lung Antibodies	>4 publications with KIF2C and Lung
Testis Antibodies	>4 publications with KIF2C and Testis
Brain Antibodies	>3 publications with KIF2C and Brain
Stomach Antibodies	>2 publications with KIF2C and Stomach
Intestine Antibodies	>2 publications with KIF2C and Intestine
Lymph Node Antibodies	>2 publications with KIF2C and Lymph Node
Lymph Antibodies	>2 publications with KIF2C and Lymph
Muscle Antibodies	>1 publications with KIF2C and Muscle
Liver Antibodies	>1 publications with KIF2C and Liver