• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CD70 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225654

Rat anti Mouse CD70 antibody, clone FR70 recognizes mouse CD70, a 30-33 kDa type II transmembrane protein belonging to the TNF superfamily. CD70 is not expressed on resting T cells and B cells but expression is induced on activation. Interaction of CD70 with… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
CD70, Monoclonal Antibody
Full Product Name
Rat Anti Mouse CD70: RPE
Product Gene Name
Product Synonym Names
CD70 antibody (FR70)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
FR70
Host
Rat
Species Reactivity
Mouse
Form/Format
Lyophilized
Purity/Purification
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preparation and Storage
Prior to reconstitution store at 4 degree C. After reconstitution store at 4 degree C. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
3D Structure
ModBase 3D Structure for O55237
Immunogen
A20 mouse B cell lymphoma cell line
Conjugation
RPE
Reconstitution
Reconstitute with 1.0 ml distilled water Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Pre-Lyophilization Buffer
Phosphate Buffered Saline
Fusion Partners
Spleen cells from immunized F344/DuCrj rats were fused with cells of the mouse P3U1 myeloma cell line.
Preservative Stabilizers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
5% Sucrose
Applications Tested/Suitable for anti-CD70 antibody
Flow Cytometry (FC/FACS)

Testing Data of anti-CD70 antibody

Staining of LPS activated mouse spleen cells with Rat anti Mouse CD70
Rat Anti-CD70 Monoclonal Antibody – Cat# MBS225654

Testing Data of anti-CD70 antibody

Staining of LPS activated mouse spleen cells with Alexa Fluor 647 conjugated Rat anti Mouse CD70:
Rat Anti-CD70 Monoclonal Antibody, Testing Data – Cat# MBS225654

Testing Data of anti-CD70 antibody

Staining of LPS activated mouse spleen cells with Alexa Fluor 488 conjugated Rat anti Mouse CD70
Rat Anti-CD70 Monoclonal Antibody, Testing Data – Cat# MBS225654

Testing Data of anti-CD70 antibody

Staining of LPS stimulated mouse spleen cells with biotinylated Rat anti-Mouse CD70
Rat Anti-CD70 Monoclonal Antibody, Testing Data – Cat# MBS225654

Other Notes

Small volumes of anti-CD70 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD70 purchase

MBS225654 is an antibody targeting CD70. Also known as Rat Anti Mouse CD70: RPE. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD70. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
CD70 antigen
NCBI Official Synonym Full Names
CD70 antigen
NCBI Official Symbol
Cd70
NCBI Official Synonym Symbols
Cd27l; CD27LG; Tnfsf7; Tnlg8a
UniProt Protein Name
CD70 antigen
UniProt Synonym Protein Names
CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
Protein Family
UniProt Gene Name
Cd70
UniProt Synonym Gene Names
Cd27l; Cd27lg; Tnfsf7; CD27-L
UniProt Entry Name
CD70_MOUSE
NCBI Protein Information
CD70 antigen

UniProt Comments for CD70

CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family.

Protein type: Cytokine; Membrane protein, integral

Cellular Component: extracellular space; membrane; integral to membrane; plasma membrane

Molecular Function: protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000