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CD1c Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225779

Mouse anti Human CD1c, clone L161, recognizes CD1c. CD1c, along with CD1a and CD1b, belong to group 1 of the CD1 family of glycoproteins. These MHC-like glycoproteins serve as lipid-presenting molecules for a subset of T cells (Porcelli et al. 1989).CD1c is… More details

$465 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD1c, Monoclonal Antibody
Full Product Name
Mouse Anti Human CD1c
Product Gene Name
anti-CD1c antibody
Product Synonym Names
CD1c antibody, L161
Clonality
Monoclonal
Isotype
IgG1
Clone Number
L161
Host
Mouse
Species Reactivity
Human
Form/Format
Purified IgG - Liquid
Purity/Purification
>95% by SDS PAGE
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE.
This product should be stored undiluted.
OMIM
188340
3D Structure
ModBase 3D Structure for P29017
Immunogen
Human thymocytes
Preservative Stabilizers
<0.1% Sodium Azide (NaN3)
Buffer Solution
Phosphate Buffered Saline
Applications Tested/Suitable for anti-CD1c antibody
Immunohistochemistry (IHC) Frozen, Flow Cytometry (FC/FACS), Immunoprecipitation (IP)

Testing Data of anti-CD1c antibody

Surface Staining of human peripheral blood cells with Mouse anti Human CD1c:RPE
Mouse Anti-CD1c Monoclonal Antibody – Cat# MBS225779

Testing Data of anti-CD1c antibody

Figure A. FITC conjugated Mouse anti Human CD19 and RPE conjugated mouse IgG1 isotype control . Figure B. FITC conjugated Mouse anti Human CD19 and RPE conjugated Mouse anti Human CD1c . All experiments were performed on human peripheral blood lymphocytes blocked with 10% human serum, gated on live single cell lymphocytes. Data acquired on the ZE5 Cell Analyzer.
Mouse Anti-CD1c Monoclonal Antibody, Testing Data – Cat# MBS225779

Other Notes

Small volumes of anti-CD1c antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD1c purchase

MBS225779 is an antibody targeting CD1c. Also known as Mouse Anti Human CD1c. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD1c. It may not necessarily be applicable to this product.

NCBI GI #
110618227
NCBI GeneID
911
NCBI Accession #
NP_001756.2
UniProt Primary Accession #
P29017
UniProt Related Accession #
P29017
GenBank Nucleotide #
NP_001756.2
NCBI Official Full Name
T-cell surface glycoprotein CD1c
NCBI Official Synonym Full Names
CD1c molecule
NCBI Official Symbol
CD1C
NCBI Official Synonym Symbols
R7; CD1; CD1A; BDCA1
UniProt Protein Name
T-cell surface glycoprotein CD1c
UniProt Synonym Protein Names
CD_antigen: CD1c
Protein Family
T-cell surface glycoprotein
UniProt Gene Name
CD1C
UniProt Entry Name
CD1C_HUMAN
NCBI Protein Information
T-cell surface glycoprotein CD1c

NCBI Summary for CD1c

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
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Research Articles on CD1c

1. The expression of histones, small nucleolar RNA H/ACA box (SNORA) and small nucleolar RNA C/D/box (SNORD), and long non-coding RNA (lncRNA) is also substantially upregulated in the DCs from aged. In contrast, the antigen-presenting and energy generating pathways are downregulated

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD1c antibody

 Reference Product  PubMed Publications
 CD4 antibody  >103 publications with CD1c and CD4
 CD40 antibody  >42 publications with CD1c and CD40
 CD86 antibody  >42 publications with CD1c and CD86
 CD83 antibody  >39 publications with CD1c and CD83
 CD19 antibody  >23 publications with CD1c and CD19
 CLEC4C antibody  >17 publications with CD1c and CLEC4C
 CD209 antibody  >6 publications with CD1c and CD209

Pathways associated with anti-CD1c antibody

 Products by Pathway  Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram

Diseases associated with anti-CD1c antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >43 publications with CD1c and Necrosis
 Skin Diseases Antibodies  >42 publications with CD1c and Skin Diseases
 Nervous System Diseases Antibodies  >18 publications with CD1c and Nervous System Diseases
 Liver Diseases Antibodies  >9 publications with CD1c and Liver Diseases
 Kidney Diseases Antibodies  >9 publications with CD1c and Kidney Diseases
 Anemia Antibodies  >5 publications with CD1c and Anemia
 Hepatitis C Antibodies  >5 publications with CD1c and Hepatitis C
 Muscular Diseases Antibodies  >3 publications with CD1c and Muscular Diseases
 Fetal Diseases Antibodies  >3 publications with CD1c and Fetal Diseases
 Pre-Eclampsia Antibodies  >3 publications with CD1c and Pre-Eclampsia

Organs/Tissues associated with anti-CD1c antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >356 publications with CD1c and Blood
 Bone Antibodies  >35 publications with CD1c and Bone
 Lymph Node Antibodies  >33 publications with CD1c and Lymph Node
 Bone Marrow Antibodies  >30 publications with CD1c and Bone Marrow
 Lung Antibodies  >25 publications with CD1c and Lung
 Thymus Antibodies  >21 publications with CD1c and Thymus
 Spleen Antibodies  >20 publications with CD1c and Spleen
 Liver Antibodies  >19 publications with CD1c and Liver
 Intestine Antibodies  >16 publications with CD1c and Intestine
 Vascular Antibodies  >15 publications with CD1c and Vascular
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