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CD352 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS225853

Mouse anti Human CD352, clone hSF6.4.20 recognizes the human CD352 antigen, also known as SLAM family member 6 (SLAMF6), activating NK receptor and NK-T-B-antigen.CD352 is a 60 kDa, transmembrane glycoprotein member of the signaling lymphocyte activating… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD352, Monoclonal Antibody
Full Product Name
Mouse Anti Human CD352: RPE
Product Gene Name
Product Synonym Gene Name
SLAMF6
Product Synonym Names
CD352 antibody, hSF6.4.20
Clonality
Monoclonal
Isotype
IgG1
Clone Number
hSF6.4.20
Host
Mouse
Species Reactivity
Human
Form/Format
Purified IgG conjugated to R. Phycoerythrin (RPE) - Lyophilized
Purity/Purification
Purified IgG prepared by affinity chromatography on Protein A.
Preparation and Storage
Prior to reconstitution Store at 4 degree C.
After reconstitution Store at 4 degree C. DO NOT FREEZE.
This product should be stored undiluted.
This product is photosensitive and should be protected from light.
OMIM
606446
3D Structure
ModBase 3D Structure for Q96DU3
Immunogen
Human CD352 (SLAMF6) transfected cell line
Preservative Stabilizers
0.09% Sodium Azide (NaN3) 1% Bovine Serum Albumin 5% Sucrose
Reconstitution
Reconstitute with 1.0 ml distilled water.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial.
Applications Tested/Suitable for anti-CD352 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD352 antibody
FC/FACS: Min. Dilution: Neat
Use 10ul of the suggested working dilution to label 106 cells in 100ul

Testing Data of anti-CD352 antibody

FITC conjugated Rat anti Human CD8 and purified Mouse IgG1 isotype control detected with RPE conjugated Goat anti Mouse IgG1 . Figure B. FITC conjugated Rat anti Human CD8 and purified Mouse anti Human CD352 detected with RPE conjugated Goat anti Mouse IgG1 . All experiments performed on human blood gated on live single cell lymphocytes in the presence of human serum. Data acquired on the ZE5 Cell Analyzer
Mouse Anti-CD352 Monoclonal Antibody – Cat# MBS225853

Other Notes

Small volumes of anti-CD352 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD352 purchase

MBS225853 is an antibody targeting CD352. Also known as Mouse Anti Human CD352: RPE. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD352. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SLAM family member 6 isoform 1
NCBI Official Synonym Full Names
SLAM family member 6
NCBI Official Symbol
SLAMF6
NCBI Official Synonym Symbols
KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000
UniProt Protein Name
SLAM family member 6
UniProt Synonym Protein Names
Activating NK receptor; NK-T-B-antigen; NTB-A; CD_antigen: CD352
Protein Family
UniProt Gene Name
SLAMF6
UniProt Synonym Gene Names
KALI; NTB-A
UniProt Entry Name
SLAF6_HUMAN
NCBI Protein Information
SLAM family member 6

NCBI Summary for CD352

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]
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UniProt Comments for CD352

SLAMF6: Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: receptor activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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